Literature DB >> 25783210

Immediate Reconstruction with Autologous fat Transfer Following Breast-Conserving Surgery.

Jorge Villanova Biazus1, Christiane Cardoso Falcão, Angela Ceconello Parizotto, Camile Cesa Stumpf, José Antônio Crespo Cavalheiro, Fernando Schuh, Rodrigo Cericatto, Ângela Erguy Zucatto, Márcia Portela Melo.   

Abstract

This study explores the technical viability of autologous fat grafting for immediate partial breast reconstruction following the primary conservative surgery for breast cancer; restoring volume, shape, and symmetry to the treated breast. We analyze the impact in relation to mammographic follow-up and the subjective degree of satisfaction with esthetic results and although we didn't have any local failure during the observation period; we understand that is too early for any kind of conclusion. From June of 2010 to July of 2011, 20 patients were selected for breast-conserving surgery (BCS) with partial breast reconstruction with autologous fat grafting performed during the same operation by the same medical team. The fat graft was injected in the subcutaneous and intraglandular breast tissue around the resected area. We performed an overcorrection, predicting a resorbing of about 30-50% of the volume grafted. All patients received the literature-based recommendations for breast cancer treatment with complementary radiotherapy. The follow-up period after the completion of radiotherapy ranged from 13 to 29 months. The average volume grafted was 121 cc and it was 2.1 times larger than the resected volume. The esthetic scores were considered very good or good in the majority of cases. Mammograms were taken every 6 months after radiotherapy and only one patient had a mammogram classified as BI-RADS 3, suggesting fat necrosis. The remaining patients were classified as BI-RADS 2. Immediate autologous fat grafting is a promising technique for partial breast reconstruction after BCS. It is associated with high patient and physician satisfaction. It is an alternative for reconstruction of small- and medium-sized breasts. This technique has the advantage that enables the reconstruction of defects in areas difficult to repair, particularly in the upper inner quadrants. It also may reduce the need for major glandular or myocutaneous flaps mobilization.
© 2015 Wiley Periodicals, Inc.

Entities:  

Keywords:  autologous fat grafting; breast cancer; breast reconstruction; breast-conserving surgery; lipofilling

Mesh:

Year:  2015        PMID: 25783210     DOI: 10.1111/tbj.12397

Source DB:  PubMed          Journal:  Breast J        ISSN: 1075-122X            Impact factor:   2.431


  11 in total

Review 1.  Autologous fat grafting in breast reconstruction: implications for follow-up and surveillance.

Authors:  Summer E Hanson; Sahil K Kapur; Rosa F Hwang; Mark S Dryden
Journal:  Gland Surg       Date:  2021-01

2.  Receptor for hyaluronan mediated motility (RHAMM/HMMR) is a novel target for promoting subcutaneous adipogenesis.

Authors:  S B Bahrami; C Tolg; T Peart; C Symonette; M Veiseh; J U Umoh; D W Holdsworth; J B McCarthy; L G Luyt; M J Bissell; A Yazdani; E A Turley
Journal:  Integr Biol (Camb)       Date:  2017-02-20       Impact factor: 2.192

3.  Clinical study of the feasibility, complications, and cosmetic outcomes of immediate autologous fat grafting during breast-conserving surgery for early-stage breast cancer in China.

Authors:  Hongyuan Li; Yuanyuan Wang; Dejuan Yang; Jean Yves Petit; Guosheng Ren
Journal:  Gland Surg       Date:  2021-08

Review 4.  Oncological safety of reconstruction with autologous fat grafting in breast cancer patients: a systematic review and meta-analysis.

Authors:  Jiale Sun; He Liang; Dongcai Lin; Bing Han; Tiran Zhang; Jidong Gao
Journal:  Int J Clin Oncol       Date:  2022-07-05       Impact factor: 3.850

5.  A Comparison of Two Fat Grafting Methods on Operating Room Efficiency and Costs.

Authors:  Allen Gabriel; G Patrick Maxwell; Leah Griffin; Manish C Champaneria; Mousam Parekh; David Macarios
Journal:  Aesthet Surg J       Date:  2016-10-11       Impact factor: 4.283

6.  Meta-analysis of the oncological safety of autologous fat transfer after breast cancer.

Authors:  T K Krastev; S J Schop; J Hommes; A A Piatkowski; E M Heuts; R R W J van der Hulst
Journal:  Br J Surg       Date:  2018-06-05       Impact factor: 6.939

7.  Plasticity of patient-matched normal mammary epithelial cells is dependent on autologous adipose-derived stem cells.

Authors:  Annika Kengelbach-Weigand; Kereshmeh Tasbihi; Pamela L Strissel; Rafael Schmid; Jasmin Monteiro Marques; Justus P Beier; Matthias W Beckmann; Reiner Strick; Raymund E Horch; Anja M Boos
Journal:  Sci Rep       Date:  2019-07-24       Impact factor: 4.379

Review 8.  Adipose regeneration and implications for breast reconstruction: update and the future.

Authors:  Emman J Combellack; Zita M Jessop; Naghmeh Naderi; Michelle Griffin; Thomas Dobbs; Amel Ibrahim; Stephen Evans; Stephanie Burnell; Shareen H Doak; Iain S Whitaker
Journal:  Gland Surg       Date:  2016-04

Review 9.  Oncoplastic Breast Surgery: What, When and for Whom?

Authors:  R Douglas Macmillan; Stephen J McCulley
Journal:  Curr Breast Cancer Rep       Date:  2016-05-03

10.  A Comparison of Fat Graft Processing Techniques: Outcomes in 1,158 Procedures in Prosthetic Breast Reconstructions.

Authors:  Wen-Kuan Chiu; Megan Fracol; Lauren N Feld; Cecil S Qiu; John Y S Kim
Journal:  Plast Reconstr Surg Glob Open       Date:  2019-11-12
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