Literature DB >> 2578225

Myosin: a link between streptococci and heart.

K Krisher, M W Cunningham.   

Abstract

Murine monoclonal antibodies to Streptococcus pyogenes reacted with skeletal muscle myosin. High molecular weight proteins in extracts of human heart tissue that reacted with an antibody to S. pyogenes also reacted with a monoclonal antibody to ventricular myosin. Adsorption of the antibody to streptococci with S. pyogenes simultaneously removed reactivity of the antibody for either S. pyogenes or myosin. These results indicate that myosin shares immunodeterminants with a component of S. pyogenes.

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Year:  1985        PMID： 2578225     DOI： 10.1126/science.2578225

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  69 in total

1.  Autoantibodies in the sera of patients with rheumatic heart disease: characterization of myocardial antigens by two-dimensional immunoblotting and N-terminal sequence analysis.

Authors:  D Tontsch; S Pankuweit; B Maisch
Journal:  Clin Exp Immunol       Date:  2000-08       Impact factor: 4.330

Review 2.  Cardiac myosin and the TH1/TH2 paradigm in autoimmune myocarditis.

Authors:  M W Cunningham
Journal:  Am J Pathol       Date:  2001-07       Impact factor: 4.307

3.  Anti-endothelial cell antibodies in rheumatic heart disease.

Authors:  V Scalzi; H Abu Hadi; C Alessandri; C Croia; V Conti; L Agati; A Angelici; V Riccieri; C Meschini; A Al-Motarreb; A Al-Ansi; G Valesini
Journal:  Clin Exp Immunol       Date:  2010-09       Impact factor: 4.330

Review 4.  Molecular mimicry--hypothesis or reality?

Authors:  N Tsuchiya; R C Williams
Journal:  West J Med       Date:  1992-08

5.  Molecular mimicry and myasthenia gravis. An autoantigenic site of the acetylcholine receptor alpha-subunit that has biologic activity and reacts immunochemically with herpes simplex virus.

Authors:  P L Schwimmbeck; T Dyrberg; D B Drachman; M B Oldstone
Journal:  J Clin Invest       Date:  1989-10       Impact factor: 14.808

Review 6.  Unresolved issues in theories of autoimmune disease using myocarditis as a framework.

Authors:  Robert Root-Bernstein; DeLisa Fairweather
Journal:  J Theor Biol       Date:  2014-12-04       Impact factor: 2.691

Review 7.  Molecular Mimicry, Autoimmunity, and Infection: The Cross-Reactive Antigens of Group A Streptococci and their Sequelae.

Authors:  Madeleine W Cunningham
Journal:  Microbiol Spectr       Date:  2019-07

8.  Cloning and sequence analysis of a gene encoding a 67-kilodalton myosin-cross-reactive antigen of Streptococcus pyogenes reveals its similarity with class II major histocompatibility antigens.

Authors:  K S Kil; M W Cunningham; L A Barnett
Journal:  Infect Immun       Date:  1994-06       Impact factor: 3.441

9.  Autoanti-idiotypes exhibit mimicry of myocyte antigens in virus-induced myocarditis.

Authors:  R E Paque; R Miller
Journal:  J Virol       Date:  1991-01       Impact factor: 5.103

10.  Fc-receptor and M-protein genes of group A streptococci are products of gene duplication.

Authors:  D G Heath; P P Cleary
Journal:  Proc Natl Acad Sci U S A       Date:  1989-06       Impact factor: 11.205
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