Literature DB >> 25781655

Limonoids and Triterpenoids from Dysoxylum mollissimum var. glaberrimum.

Mei-Ling Han1, Jin-Xin Zhao1, Hong-Chun Liu1, Gang Ni1, Jian Ding1, Sheng-Ping Yang1, Jian-Min Yue1.   

Abstract

Seven new limonoids, dysomollides A-G (1-7), and two new cycloapotirucallane-type triterpenoids, dysomollins A and B (8 and 9), together with three known compounds, dysoxylumin A (10) and toonapubesins A (11) and B (12), were isolated from the twigs of Dysoxylum mollissimum var. glaberrimum. The structures of 1-9 were elucidated on the basis of spectroscopic methods. Compound 10 showed inhibitory activity against A549 cells with an IC50 value of 2.1 μM, and compound 11 exhibited activity against P388 cells with an IC50 value of 6.7 μM.

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Year:  2015        PMID: 25781655     DOI: 10.1021/np500967k

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  1 in total

Review 1.  Triterpenoids from Dysoxylum genus and their biological activities.

Authors:  Al Arofatus Naini; Tri Mayanti; Unang Supratman
Journal:  Arch Pharm Res       Date:  2022-01-31       Impact factor: 4.946

  1 in total

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