BACKGROUND AND OBJECTIVE: An estimated 25-40% of patients with chronic obstructive pulmonary disease (COPD) have never smoked. We investigated the prevalence and patient characteristics of COPD in non-smokers from Vietnam and Indonesia. METHODS: This population-based cross-sectional survey of participants from urban and rural Vietnam and Indonesia used a stratified multistage cluster sampling design, with sample and population weights applied to ensure representativeness. Participants were female or male (recruited in the ratio 2:1) non-smokers, 40 years or older and able to perform a spirometry test. Spirometry was performed at a single study visit. Other clinical information was collected via standardized questionnaires. RESULTS: The 1506 evaluable participants were approximately equally distributed between Vietnam and Indonesia, and rural and urban areas. Overall prevalence of COPD was found to be 6.9% (95% confidence interval (CI): 5.7-8.3), with almost three times higher prevalence in men than women (12.9% (95% CI: 9.1-18.0) vs 4.4% (95% CI: 3.0-6.5)). We found higher rates of COPD in Vietnam than Indonesia (8.1% (95% CI: 5.8-11.3) vs 6.3% (95% CI: 4.8-8.3)), with a particularly high prevalence in urban Vietnam (11.1% (95% CI: 8.1-15.1)). Very few participants (6%) diagnosed to have COPD during the study had been previously diagnosed with COPD. Respiratory symptoms and lower health-related quality of life were more common in participants with COPD. CONCLUSIONS: The prevalence of COPD in non-smoking individuals from rural and urban Vietnam and Indonesia was 6.9%, of which a significant proportion (94%) were previously undiagnosed.
BACKGROUND AND OBJECTIVE: An estimated 25-40% of patients with chronic obstructive pulmonary disease (COPD) have never smoked. We investigated the prevalence and patient characteristics of COPD in non-smokers from Vietnam and Indonesia. METHODS: This population-based cross-sectional survey of participants from urban and rural Vietnam and Indonesia used a stratified multistage cluster sampling design, with sample and population weights applied to ensure representativeness. Participants were female or male (recruited in the ratio 2:1) non-smokers, 40 years or older and able to perform a spirometry test. Spirometry was performed at a single study visit. Other clinical information was collected via standardized questionnaires. RESULTS: The 1506 evaluable participants were approximately equally distributed between Vietnam and Indonesia, and rural and urban areas. Overall prevalence of COPD was found to be 6.9% (95% confidence interval (CI): 5.7-8.3), with almost three times higher prevalence in men than women (12.9% (95% CI: 9.1-18.0) vs 4.4% (95% CI: 3.0-6.5)). We found higher rates of COPD in Vietnam than Indonesia (8.1% (95% CI: 5.8-11.3) vs 6.3% (95% CI: 4.8-8.3)), with a particularly high prevalence in urban Vietnam (11.1% (95% CI: 8.1-15.1)). Very few participants (6%) diagnosed to have COPD during the study had been previously diagnosed with COPD. Respiratory symptoms and lower health-related quality of life were more common in participants with COPD. CONCLUSIONS: The prevalence of COPD in non-smoking individuals from rural and urban Vietnam and Indonesia was 6.9%, of which a significant proportion (94%) were previously undiagnosed.
Authors: Julia Schröders; Stig Wall; Mohammad Hakimi; Fatwa Sari Tetra Dewi; Lars Weinehall; Mark Nichter; Maria Nilsson; Hari Kusnanto; Ekowati Rahajeng; Nawi Ng Journal: PLoS One Date: 2017-06-20 Impact factor: 3.240
Authors: Hai Minh Vu; Long Hoang Nguyen; Tung Hoang Tran; Kiet Tuan Huy Pham; Hai Thanh Phan; Hieu Ngoc Nguyen; Bach Xuan Tran; Carl A Latkin; Cyrus S H Ho; Roger C M Ho Journal: Int J Environ Res Public Health Date: 2019-09-27 Impact factor: 3.390
Authors: Ary I Savitri; Nikmah S Idris; Wahyuni Indawati; Siti Rizny F Saldi; Dwirani Amelia; Mohammad Baharuddin; Sudigdo Sastroasmoro; Diederick E Grobbee; Cuno S P M Uiterwaal Journal: Trials Date: 2016-06-02 Impact factor: 2.279
Authors: Ha Thanh Nguyen; Peter F Collins; Toby G Pavey; Nhung Viet Nguyen; Tuong Duy Pham; Danielle L Gallegos Journal: Int J Chron Obstruct Pulmon Dis Date: 2019-01-14
Authors: Thu-Anh Nguyen; Yen Ngoc Pham; Nhung Phuong Doan; Thao Huong Nguyen; Toan Thanh Do; Giap Van Vu; Guy B Marks; Shannon McKinn; Joel Negin; Sarah Bernays; Greg J Fox Journal: BMC Public Health Date: 2021-06-15 Impact factor: 3.295