OBJECTIVES/HYPOTHESIS: As survival rates in oropharyngeal cancer improve, long-term functional outcomes are increasingly important to understand. We report long-term functional outcomes in a cohort of surviving patients with oropharyngeal squamous cell carcinoma treated with primary surgery ± radiotherapy. STUDY DESIGN: Cross-sectional study. METHODS: Patients undergoing primary surgery for oropharyngeal cancer in Oxford, United Kingdom, between 2000 and 2010 were identified. The University of Washington Quality-of- Life and MD Anderson Dysphagia Inventory questionnaires were sent to all patients. Multivariate analysis was performed to determine the relationship between clinical factors and swallowing outcomes. RESULTS: Twenty percent of patients required gastrostomy-tube placement (mean feed duration, 114 days). On multivariate analysis, increased age, advanced T stage, and an open surgical approach were associated with significantly reduced quality-of-life scores. CONCLUSIONS: Mean functional scores were comparable to previously published series of patients treated with primary surgery. Gastrostomy insertion rate was lower than in many previously published studies. Furthermore, specific variables have been identified that are associated with adverse functional outcome.
OBJECTIVES/HYPOTHESIS: As survival rates in oropharyngeal cancer improve, long-term functional outcomes are increasingly important to understand. We report long-term functional outcomes in a cohort of surviving patients with oropharyngeal squamous cell carcinoma treated with primary surgery ± radiotherapy. STUDY DESIGN: Cross-sectional study. METHODS:Patients undergoing primary surgery for oropharyngeal cancer in Oxford, United Kingdom, between 2000 and 2010 were identified. The University of Washington Quality-of- Life and MD Anderson Dysphagia Inventory questionnaires were sent to all patients. Multivariate analysis was performed to determine the relationship between clinical factors and swallowing outcomes. RESULTS: Twenty percent of patients required gastrostomy-tube placement (mean feed duration, 114 days). On multivariate analysis, increased age, advanced T stage, and an open surgical approach were associated with significantly reduced quality-of-life scores. CONCLUSIONS: Mean functional scores were comparable to previously published series of patients treated with primary surgery. Gastrostomy insertion rate was lower than in many previously published studies. Furthermore, specific variables have been identified that are associated with adverse functional outcome.
Authors: Ryan P Goepfert; Jan S Lewin; Martha P Barrow; Carla L Warneke; Clifton D Fuller; Stephen Y Lai; Randal S Weber; Katherine A Hutcheson Journal: Dysphagia Date: 2017-08-23 Impact factor: 3.438
Authors: Hemail M Alsubaie; Suhail I Sayed; Albaraa Y Alsini; Haddad H Alkaff; Osama A Margalani; Ahmed Abu-Zaid; Omar A Abu-Suliman; Ameen Z Alherabi; Saeed A Alghamdi; Essam Saleh; Mohammad A Alessa; Sherif K Abdelmonim Journal: Dysphagia Date: 2021-08-24 Impact factor: 2.733
Authors: Vivek R Varma; Antoine Eskander; Stephen Y Kang; Bhavna Kumar; Nicole V Brown; Songzhu Zhao; Guy Brock; Amit Agrawal; Ricardo L Carrau; Matthew O Old; Enver Ozer; James W Rocco; David E Schuller; Peter T Dziegielewski; Michael J Cipolla; Theodoros N Teknos Journal: Laryngoscope Date: 2018-09-08 Impact factor: 3.325
Authors: Hani Z Marzouki; Vincent L Biron; Peter T Dziegielewski; Andrew Ma; Jason Vaz; Gabriela Constantinescu; Jeffrey Harris; Daniel O'Connell; Hadi Seikaly Journal: J Otolaryngol Head Neck Surg Date: 2018-09-19