Literature DB >> 2578120

Effect of phenethyl alcohol on Staphylococcus aureus alpha-lysin production.

K Y Lee, T H Birkbeck.   

Abstract

Phenethyl alcohol, at the maximum concentration which did not inhibit growth (0.3% [vol/vol]), inhibited the production of alpha-lysin and exoproteases but not that of delta-lysin in Staphylococcus aureus Wood 46. The inhibition of alpha-lysin was reversible, and transient accumulation of cell-associated alpha-lysin occurred in the presence of PEA. A precursor of alpha-lysin ca. 3,000 daltons larger than extracellular alpha-lysin was immunologically detected in the sodium dodecyl sulfate extracts of membranes and whole cells of phenethyl alcohol-treated S. aureus cultures. Also, a degraded form of alpha-lysin was detected in membranes prepared from cells lysed by lysostaphin but not in membranes from cells lysed with an X-press.

Entities:  

Mesh：

Substances：

Year:  1985        PMID： 2578120      PMCID： PMC261484          DOI： 10.1128/iai.47.1.112-117.1985

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  29 in total

1.  Extreme sensitivity of staphylococcal enterotoxin B and C production to inhibition by cerulenin.

Authors:  R A Altenbern
Journal:  Antimicrob Agents Chemother       Date:  1977-05       Impact factor: 5.191

2.  Mechanistic aspects of the transfer of nascent periplasmic proteins across the cytoplasmic membrane in Escherichia coli.

Authors:  J M Pagès; M Piovant; S Varenne; C Lazdunski
Journal:  Eur J Biochem       Date:  1978-05-16

3.  Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

Authors:  H Towbin; T Staehelin; J Gordon
Journal:  Proc Natl Acad Sci U S A       Date:  1979-09       Impact factor: 11.205

4.  Assay of staphylococcal delta-haemolysin with fish erythrocytes.

Authors:  L P Chao; T H Birkbeck
Journal:  J Med Microbiol       Date:  1978-08       Impact factor: 2.472

5.  Lipid fluidity-dependent biosynthesis and assembly of the outer membrane proteins of E. coli.

Authors:  J M DiRienzo; M Inouye
Journal:  Cell       Date:  1979-05       Impact factor: 41.582

6.  Transport and processing of staphylococcal alpha-toxin.

Authors:  R K Tweten; K K Christianson; J J Iandolo
Journal:  J Bacteriol       Date:  1983-11       Impact factor: 3.490

7.  Translocation and assembly of outer membrance proteins of Escherichia coli. Selective accumulation of precursors and novel assembly intermediates caused by phenethyl alcohol.

Authors:  S Halegoua; M Inouye
Journal:  J Mol Biol       Date:  1979-05-05       Impact factor: 5.469

8.  Procaine, a local anesthetic interacting with the cell membrane, inhibits the processing of precursor forms of periplasmic proteins in Escherichia coli.

Authors:  C Lazdunski; D Baty; J M Pagès
Journal:  Eur J Biochem       Date:  1979-05-02

9.  Effects of phenethyl alcohol on phospholipid metabolism in Escherichia coli.

Authors:  W D Nunn; B E Tropp
Journal:  J Bacteriol       Date:  1972-01       Impact factor: 3.490

10.  Lipid monolayers: influence of lipid film and urea on the surface activity of staphylococcal alpha-toxin.

Authors:  G Colacicco; A R Buckelew
Journal:  Lipids       Date:  1971-08       Impact factor: 1.880
View more
  2 in total

Review 1.  Alpha-toxin of Staphylococcus aureus.

Authors:  S Bhakdi; J Tranum-Jensen
Journal:  Microbiol Rev       Date:  1991-12

2.  Surfactants, aromatic and isoprenoid compounds, and fatty acid biosynthesis inhibitors suppress Staphylococcus aureus production of toxic shock syndrome toxin 1.

Authors:  Peter J McNamara; Rae Ellen Syverson; Kathy Milligan-Myhre; Olga Frolova; Sarah Schroeder; Joshua Kidder; Thanh Hoang; Richard A Proctor
Journal:  Antimicrob Agents Chemother       Date:  2009-02-17       Impact factor: 5.191
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.