Nagaraj Basavegowda1, Gowri Dhanya Kumar1, Bozena Tyliszczak2, Zbigniew Wzorek3, Agnieszka Sobczak-Kupiec3. 1. Department of Biotechnology, Shridevi Institute of Engineering & Technology, Tumkur, Karnataka, India. 2. Department of Chemistry and Technology of Polymers, Cracow University of Technology, Cracow, Poland. 3. Institute of Inorganic Chemistry and Technology, Cracow University of Technology, Cracow, Poland.
Abstract
INTRODUCTION: Novel approaches for the synthesis of gold nanoparticles (AuNPs) are of great importance due to its vast spectrum of applications in diverse fields, including medical diagnostics and therapeutics. Te presented study reports the successful AuNPs' synthesis using Artocarpus heterophyllus Lam. extract, and provides detailed characterization and evaluation of its antibacterial potential. OBJECTIVE: The aim was to develop a cost-effective and environmentally friendly synthesis method of gold nanoparticles using aqueous fruit extract of Artocarpus heterophyllus Lam. as a reducing and capping agent, which has proven activity against human pathogens, such as microbial species E.coli and Streptobacillus sps. MATERIALS AND METHOD: Characterizations were carried out using ultraviolet-visible (UV-Vis) spectrophotometry, scanning electron microscopy (SEM), energy dispersive X-ray and Fourier-Transform infra-red spectroscopy (FT-IR). RESULTS: SEM images showed the formation of gold nanoparticles with an average size of 20-25 nm. Spectra collected while infra-red analysis contained broad peaks in ranges from 4000-400 cm -1 . CONCLUSIONS: It can be concluded that the fruit of Artocarpus heterophyllus Lam. can be good source for synthesis of gold nanoparticles which showed antimicrobial activity against investigated microbes, in particul E. coli, and Streptobacillus. An important outcome of this study will be the development of value-added products from the medicinal plant Artocarpus heterophyllus Lam. for the biomedical and nanotechnology-based industries.
INTRODUCTION: Novel approaches for the synthesis of gold nanoparticles (AuNPs) are of great importance due to its vast spectrum of applications in diverse fields, including medical diagnostics and therapeutics. Te presented study reports the successful AuNPs' synthesis using Artocarpus heterophyllus Lam. extract, and provides detailed characterization and evaluation of its antibacterial potential. OBJECTIVE: The aim was to develop a cost-effective and environmentally friendly synthesis method of gold nanoparticles using aqueous fruit extract of Artocarpus heterophyllus Lam. as a reducing and capping agent, which has proven activity against human pathogens, such as microbial species E.coli and Streptobacillus sps. MATERIALS AND METHOD: Characterizations were carried out using ultraviolet-visible (UV-Vis) spectrophotometry, scanning electron microscopy (SEM), energy dispersive X-ray and Fourier-Transform infra-red spectroscopy (FT-IR). RESULTS: SEM images showed the formation of gold nanoparticles with an average size of 20-25 nm. Spectra collected while infra-red analysis contained broad peaks in ranges from 4000-400 cm -1 . CONCLUSIONS: It can be concluded that the fruit of Artocarpus heterophyllus Lam. can be good source for synthesis of gold nanoparticles which showed antimicrobial activity against investigated microbes, in particul E. coli, and Streptobacillus. An important outcome of this study will be the development of value-added products from the medicinal plant Artocarpus heterophyllus Lam. for the biomedical and nanotechnology-based industries.
Authors: Erin P Sproul; Seema Nandi; Eunice Chee; Supriya Sivadanam; Benjamin J Igo; Luisa Schreck; Ashley C Brown Journal: Regen Eng Transl Med Date: 2019-08-06
Authors: Miryam M Luzala; Claude K Muanga; Joseph Kyana; Justin B Safari; Eunice N Zola; Grégoire V Mbusa; Yannick B Nuapia; Jean-Marie I Liesse; Christian I Nkanga; Rui W M Krause; Aistė Balčiūnaitienė; Patrick B Memvanga Journal: Nanomaterials (Basel) Date: 2022-05-27 Impact factor: 5.719