Literature DB >> 25778660

Evaluation of fibrogenic potential of industrial multi-walled carbon nanotubes in acute aspiration experiment.

T O Khaliullin1, A A Shvedova, E R Kisin, R R Zalyalov, L M Fatkhutdinova.   

Abstract

Local inflammatory response in the lungs and fi brogenic potential of multi-walled carbon nanotubes were studied in an acute aspiration experiment in mice. The doses were chosen based on the concentration of nanotubes in the air at a workplace of the company-producer. ELISA, fl ow cytometry, enhanced darkfield microscopy, and histological examination showed that multi-walled carbon nanotubes induced local inflammation, oxidative stress, and connective tissue growth (fibrosis). Serum levels of TGF-β1 and osteopontin proteins can serve as potential exposure biomarkers.

Entities:  

Mesh：

Substances：

Year:  2015        PMID： 25778660      PMCID： PMC4592486          DOI： 10.1007/s10517-015-2835-7

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN： 0007-4888            Impact factor:   0.804


  11 in total

1.  A chemoattractant cytokine associated with granulomas in tuberculosis and silicosis.

Authors:  G J Nau; P Guilfoile; G L Chupp; J S Berman; S J Kim; H Kornfeld; R A Young
Journal:  Proc Natl Acad Sci U S A       Date:  1997-06-10       Impact factor: 11.205

Review 2.  Human respiratory tract model for radiological protection. A report of a Task Group of the International Commission on Radiological Protection.

Authors: 
Journal:  Ann ICRP       Date:  1994

3.  Oropharyngeal aspiration of a silica suspension produces a superior model of silicosis in the mouse when compared to intratracheal instillation.

Authors:  Heather F Lakatos; Heather A Burgess; Thomas H Thatcher; Michelle R Redonnet; Eric Hernady; Jacqueline P Williams; Patricia J Sime
Journal:  Exp Lung Res       Date:  2006-05       Impact factor: 2.459

4.  Respiratory toxicity of multi-wall carbon nanotubes.

Authors:  Julie Muller; François Huaux; Nicolas Moreau; Pierre Misson; Jean-François Heilier; Monique Delos; Mohammed Arras; Antonio Fonseca; Janos B Nagy; Dominique Lison
Journal:  Toxicol Appl Pharmacol       Date:  2005-09-15       Impact factor: 4.219

5.  Mouse pulmonary dose- and time course-responses induced by exposure to multi-walled carbon nanotubes.

Authors:  Dale W Porter; Ann F Hubbs; Robert R Mercer; Nianqiang Wu; Michael G Wolfarth; Krishnan Sriram; Stephen Leonard; Lori Battelli; Diane Schwegler-Berry; Sherry Friend; Michael Andrew; Bean T Chen; Shuji Tsuruoka; Morinobu Endo; Vincent Castranova
Journal:  Toxicology       Date:  2009-10-24       Impact factor: 4.221

6.  Inhalation toxicity of multiwall carbon nanotubes in rats exposed for 3 months.

Authors:  Lan Ma-Hock; Silke Treumann; Volker Strauss; Sandra Brill; Frederic Luizi; Michael Mertler; Karin Wiench; Armin O Gamer; Bennard van Ravenzwaay; Robert Landsiedel
Journal:  Toxicol Sci       Date:  2009-07-07       Impact factor: 4.849

7.  Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study.

Authors:  Craig A Poland; Rodger Duffin; Ian Kinloch; Andrew Maynard; William A H Wallace; Anthony Seaton; Vicki Stone; Simon Brown; William Macnee; Ken Donaldson
Journal:  Nat Nanotechnol       Date:  2008-05-20       Impact factor: 39.213

8.  Pulmonary fibrotic response to aspiration of multi-walled carbon nanotubes.

Authors:  Robert R Mercer; Ann F Hubbs; James F Scabilloni; Liying Wang; Lori A Battelli; Sherri Friend; Vincent Castranova; Dale W Porter
Journal:  Part Fibre Toxicol       Date:  2011-07-22       Impact factor: 9.400

9.  Inhaled carbon nanotubes reach the subpleural tissue in mice.

Authors:  Jessica P Ryman-Rasmussen; Mark F Cesta; Arnold R Brody; Jeanette K Shipley-Phillips; Jeffrey I Everitt; Earl W Tewksbury; Owen R Moss; Brian A Wong; Darol E Dodd; Melvin E Andersen; James C Bonner
Journal:  Nat Nanotechnol       Date:  2009-10-25       Impact factor: 39.213

10.  Extrapulmonary transport of MWCNT following inhalation exposure.

Authors:  Robert R Mercer; James F Scabilloni; Ann F Hubbs; Liying Wang; Lori A Battelli; Walter McKinney; Vincent Castranova; Dale W Porter
Journal:  Part Fibre Toxicol       Date:  2013-08-09       Impact factor: 9.400
View more
  7 in total

1.  Fibrosis biomarkers in workers exposed to MWCNTs.

Authors:  Liliya M Fatkhutdinova; Timur O Khaliullin; Olga L Vasil'yeva; Ramil R Zalyalov; Ilshat G Mustafin; Elena R Kisin; M Eileen Birch; Naveena Yanamala; Anna A Shvedova
Journal:  Toxicol Appl Pharmacol       Date:  2016-02-20       Impact factor: 4.219

2.  Comparative analysis of lung and blood transcriptomes in mice exposed to multi-walled carbon nanotubes.

Authors:  Timur O Khaliullin; Naveena Yanamala; Mackenzie S Newman; Elena R Kisin; Liliya M Fatkhutdinova; Anna A Shvedova
Journal:  Toxicol Appl Pharmacol       Date:  2020-01-22       Impact factor: 4.219

3.  Carbon Nanotubes Exposure Risk Assessment: From Toxicology to Epidemiologic Studies (Overview of the Current Problem).

Authors:  L M Fatkhutdinova; T O Khaliullin; A A Shvedova
Journal:  Nanotechnol Russ       Date:  2015-05

4.  Osteopontin enhances multi-walled carbon nanotube-triggered lung fibrosis by promoting TGF-β1 activation and myofibroblast differentiation.

Authors:  Jie Dong; Qiang Ma
Journal:  Part Fibre Toxicol       Date:  2017-06-08       Impact factor: 9.400

5.  In Vivo Activation and Pro-Fibrotic Function of NF-κB in Fibroblastic Cells During Pulmonary Inflammation and Fibrosis Induced by Carbon Nanotubes.

Authors:  Jie Dong; Qiang Ma
Journal:  Front Pharmacol       Date:  2019-10-02       Impact factor: 5.810

Review 6.  A Review on the Respiratory System Toxicity of Carbon Nanoparticles.

Authors:  Maricica Pacurari; Kristine Lowe; Paul B Tchounwou; Ramzi Kafoury
Journal:  Int J Environ Res Public Health       Date:  2016-03-15       Impact factor: 3.390

Review 7.  Nanoparticles as a Tool in Neuro-Oncology Theranostics.

Authors:  Andrea L Klein; Grant Nugent; John Cavendish; Werner J Geldenhuys; Krishnan Sriram; Dale Porter; Ross Fladeland; Paul R Lockman; Jonathan H Sherman
Journal:  Pharmaceutics       Date:  2021-06-24       Impact factor: 6.321
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.