Danica Tiodorovic-Zivkovic1, Giuseppe Argenziano2, Aimilios Lallas2, Luc Thomas3, Aleksandra Ignjatovic4, Harold Rabinovitz5, Elvira Moscarella2, Caterina Longo2, Rainer Hofmann-Wellenhof6, Iris Zalaudek7. 1. Clinic of Dermatovenereology, Clinical Center of Nis Medical Faculty, University of Nis, Nis, Serbia. 2. Skin Cancer Unit, Arcispedale S. Maria Nuova, IRCCS (Istituto Di Ricovero e Cura a Carattere Scientifico), Reggio Emilia, Italy. 3. Lyon 1 University, Dermatology Department, Centre Hospitalier Lyon Sud, Lyon, France. 4. Department of Medical Statistics, Faculty of Medicine, University of Nis, Nis, Serbia. 5. Skin and Cancer Associates, Plantation, Florida. 6. Department of Dermatology and Venereology, Medical University of Graz, Graz, Austria. 7. Department of Dermatology and Venereology, Medical University of Graz, Graz, Austria. Electronic address: iris.zalaudek@gmail.com.
Abstract
BACKGROUND: Little is known about the frequency of clinical and dermoscopic patterns of lentigo maligna (LM) in relation to specific anatomic subsites and patients characteristics. OBJECTIVE: We sought to assess the frequency of clinical and dermoscopic features of LM and to correlate them to specific anatomic subsites, and patients' age and gender. METHODS: This was a retrospective analysis of clinical and dermoscopic images of a series of consecutive, histopathologically diagnosed, facial and extrafacial LM. RESULTS: A total of 201 cases from 200 patients (mean age 69.51 ± 12.26 years) including 120 women were collected. Most cases were located on the face (n = 192, 95.5%). In 102 cases, LM presented as clinically solitary facial macule (s/LM), whereas it was associated with multiple surrounding freckles in the remaining cases. s/LM were significantly smaller (<10 vs >10 mm; P = .020) and associated with younger age compared with LM associated with multiple surrounding freckles (mean age 67.73 ± 12.68 years vs 71.34 ± 11.59 years, respectively; P = .036). Dermoscopically, gray color irrespective of a specific pattern was the most prevalent finding seen in 178 (88.6%) cases. LIMITATIONS: This was a retrospective study. CONCLUSIONS: The knowledge about patient age, patient gender, and site-related clinical features of LM associated with gray color upon dermoscopy may enhance the clinical recognition of LM.
BACKGROUND: Little is known about the frequency of clinical and dermoscopic patterns of lentigo maligna (LM) in relation to specific anatomic subsites and patients characteristics. OBJECTIVE: We sought to assess the frequency of clinical and dermoscopic features of LM and to correlate them to specific anatomic subsites, and patients' age and gender. METHODS: This was a retrospective analysis of clinical and dermoscopic images of a series of consecutive, histopathologically diagnosed, facial and extrafacial LM. RESULTS: A total of 201 cases from 200 patients (mean age 69.51 ± 12.26 years) including 120 women were collected. Most cases were located on the face (n = 192, 95.5%). In 102 cases, LM presented as clinically solitary facial macule (s/LM), whereas it was associated with multiple surrounding freckles in the remaining cases. s/LM were significantly smaller (<10 vs >10 mm; P = .020) and associated with younger age compared with LM associated with multiple surrounding freckles (mean age 67.73 ± 12.68 years vs 71.34 ± 11.59 years, respectively; P = .036). Dermoscopically, gray color irrespective of a specific pattern was the most prevalent finding seen in 178 (88.6%) cases. LIMITATIONS: This was a retrospective study. CONCLUSIONS: The knowledge about patient age, patient gender, and site-related clinical features of LM associated with gray color upon dermoscopy may enhance the clinical recognition of LM.
Authors: Amanda Regio Pereira; Marina Corral-Forteza; Helena Collgros; Mary-Ann El Sharouni; Peter M Ferguson; Richard A Scolyer; Pascale Guitera Journal: Clin Exp Dermatol Date: 2022-02-15 Impact factor: 4.481
Authors: Cristian Navarrete-Dechent; Saud Aleissa; Karen Connolly; Brian P Hibler; Stephen W Dusza; Anthony M Rossi; Erica Lee; Kishwer S Nehal Journal: J Am Acad Dermatol Date: 2020-10-20 Impact factor: 11.527