Literature DB >> 25772575

Molecular characterization of group A rotavirus strains detected in children with diarrhea admitted to Nigerian hospitals in 2013.

Giovanni Ianiro1, Roberto Delogu, Marycelin Baba, Bamidele S Oderinde, Joshua Dawurung, Franco Maria Ruggeri, Lucia Fiore.   

Abstract

Group A rotaviruses (RVA) are the leading cause of acute gastroenteritis (AGE) in children worldwide and cause up to 455,000 deaths annually, mostly in developing countries. During 2013, 66 RVAs from children with AGE admitted to four Nigerian hospitals were investigated. The G3P[6], G1P[8] and G2P[4] genotypes predominated. The VP7 and/or VP4 genes of 18 G3P[6]/[8]/[4], six G2P[4], three G12P[8]/[4], and two G1P[8] RVA strains were sequenced. The G3P[6] strains belonged to lineage G3-III and were different from G3 strains widespread in Asia. Phylogenetic analysis revealed substantial sequence conservation, suggesting continuing evolution and genomic reassortment but no zoonotic RVA transmission from animals.

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Year:  2015        PMID： 25772575     DOI： 10.1007/s00705-015-2389-z

Source DB:  PubMed          Journal:  Arch Virol        ISSN： 0304-8608            Impact factor:   2.574


  4 in total

1.  Phylogeography and evolutionary analysis of African Rotavirus a genotype G12 reveals district genetic diversification within lineage III.

Authors:  Babatunde Olanrewaju Motayo; Olukunle Oluwapamilerin Oluwasemowo; Babatunde Adebiyi Olusola; Adewale Victor Opayele; Adedayo Omotayo Faneye
Journal:  Heliyon       Date:  2019-10-21

2.  Pre-vaccine circulating group a rotavirus strains in under 5 years children with acute diarrhea during 1999-2013 in Cameroon.

Authors:  Paul Koki Ndombo; Valantine N Ndze; Charles Fokunang; Taku Nadesh Ashukem; Angeline Boula; Mina N Kinkela; Corlins E Ndode; Mapaseka L Seheri; Michael D Bowen; Diane Waku-Kouomou; Mathew D Esona
Journal:  Virology (Lond)       Date:  2017-07-25

Review 3.  Epidemiology of Rotavirus A in Nigeria: Molecular Diversity and Current Insights.

Authors:  Babatunde Olanrewaju Motayo; Adedayo Omotayo Faneye; Johnson Adekunle Adeniji
Journal:  J Pathog       Date:  2018-10-01

4.  Species A Rotavirus (RVA) Isolated from Sewage in Nigeria, 2014: Close Genetic Relatedness of Partial G, P, and NSP4 Gene Sequences Encoding G1 with Cogent Genes of Other Asian and African Rotaviruses.

Authors:  Babatunde Olanrewaju Motayo; Johnson Adekunle Adeniji; Adedayo Omotayo Faneye
Journal:  J Pathog       Date:  2018-06-24
  4 in total

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