Literature DB >> 25772290

Na+ channel function, regulation, structure, trafficking and sequestration.

Ye Chen-Izu1, Robin M Shaw, Geoffrey S Pitt, Vladimir Yarov-Yarovoy, Jon T Sack, Hugues Abriel, Richard W Aldrich, Luiz Belardinelli, Mark B Cannell, William A Catterall, Walter J Chazin, Nipavan Chiamvimonvat, Isabelle Deschenes, Eleonora Grandi, Thomas J Hund, Leighton T Izu, Lars S Maier, Victor A Maltsev, Celine Marionneau, Peter J Mohler, Sridharan Rajamani, Randall L Rasmusson, Eric A Sobie, Colleen E Clancy, Donald M Bers.   

Abstract

This paper is the second of a series of three reviews published in this issue resulting from the University of California Davis Cardiovascular Symposium 2014: Systems approach to understanding cardiac excitation-contraction coupling and arrhythmias: Na(+) channel and Na(+) transport. The goal of the symposium was to bring together experts in the field to discuss points of consensus and controversy on the topic of sodium in the heart. The present review focuses on Na(+) channel function and regulation, Na(+) channel structure and function, and Na(+) channel trafficking, sequestration and complexing.
© 2014 The Authors. The Journal of Physiology © 2014 The Physiological Society.

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Year:  2015        PMID: 25772290      PMCID: PMC4376415          DOI: 10.1113/jphysiol.2014.281428

Source DB:  PubMed          Journal:  J Physiol        ISSN: 0022-3751            Impact factor:   5.182


  113 in total

1.  Na(+) channel mutation that causes both Brugada and long-QT syndrome phenotypes: a simulation study of mechanism.

Authors:  Colleen E Clancy; Yoram Rudy
Journal:  Circulation       Date:  2002-03-12       Impact factor: 29.690

2.  Gating of the late Na+ channel in normal and failing human myocardium.

Authors:  Albertas I Undrovinas; Victor A Maltsev; John W Kyle; Norman Silverman; Hani N Sabbah
Journal:  J Mol Cell Cardiol       Date:  2002-11       Impact factor: 5.000

3.  Role of amino acid residues in transmembrane segments IS6 and IIS6 of the Na+ channel alpha subunit in voltage-dependent gating and drug block.

Authors:  Vladimir Yarov-Yarovoy; Jancy C McPhee; Diane Idsvoog; Caroline Pate; Todd Scheuer; William A Catterall
Journal:  J Biol Chem       Date:  2002-07-18       Impact factor: 5.157

4.  A calcium sensor in the sodium channel modulates cardiac excitability.

Authors:  Hanno L Tan; Sabina Kupershmidt; Rong Zhang; Svetlana Stepanovic; Dan M Roden; Arthur A M Wilde; Mark E Anderson; Jeffrey R Balser
Journal:  Nature       Date:  2002-01-24       Impact factor: 49.962

5.  Tracking voltage-dependent conformational changes in skeletal muscle sodium channel during activation.

Authors:  Baron Chanda; Francisco Bezanilla
Journal:  J Gen Physiol       Date:  2002-11       Impact factor: 4.086

Review 6.  Calmodulin signaling via the IQ motif.

Authors:  Martin Bähler; Allen Rhoads
Journal:  FEBS Lett       Date:  2002-02-20       Impact factor: 4.124

7.  Structural basis for tetrodotoxin-resistant sodium channel binding by mu-conotoxin SmIIIA.

Authors:  David W Keizer; Peter J West; Erinna F Lee; Doju Yoshikami; Baldomero M Olivera; Grzegorz Bulaj; Raymond S Norton
Journal:  J Biol Chem       Date:  2003-09-10       Impact factor: 5.157

8.  Autoregulation of connexin43 gap junction formation by internally translated isoforms.

Authors:  James W Smyth; Robin M Shaw
Journal:  Cell Rep       Date:  2013-11-07       Impact factor: 9.423

9.  Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death.

Authors:  Peter J Mohler; Jean-Jacques Schott; Anthony O Gramolini; Keith W Dilly; Silvia Guatimosim; William H duBell; Long-Sheng Song; Karine Haurogné; Florence Kyndt; Mervat E Ali; Terry B Rogers; W J Lederer; Denis Escande; Herve Le Marec; Vann Bennett
Journal:  Nature       Date:  2003-02-06       Impact factor: 49.962

10.  Non-equilibrium gating in cardiac Na+ channels: an original mechanism of arrhythmia.

Authors:  Colleen E Clancy; Michihiro Tateyama; Huajun Liu; Xander H T Wehrens; Robert S Kass
Journal:  Circulation       Date:  2003-04-14       Impact factor: 29.690

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  34 in total

1.  Sirtuin 1 regulates cardiac electrical activity by deacetylating the cardiac sodium channel.

Authors:  Ajit Vikram; Christopher M Lewarchik; Jin-Young Yoon; Asma Naqvi; Santosh Kumar; Gina M Morgan; Julia S Jacobs; Qiuxia Li; Young-Rae Kim; Modar Kassan; Jing Liu; Mohanad Gabani; Ajay Kumar; Haider Mehdi; Xiaodong Zhu; Xiaoqun Guan; William Kutschke; Xiaoming Zhang; Ryan L Boudreau; Shengchuan Dai; Daniel S Matasic; Saet-Byel Jung; Kenneth B Margulies; Vikas Kumar; Markus M Bachschmid; Barry London; Kaikobad Irani
Journal:  Nat Med       Date:  2017-02-13       Impact factor: 53.440

Review 2.  Neuronal sodium channels: emerging components of the nano-machinery of cardiac calcium cycling.

Authors:  Rengasayee Veeraraghavan; Sándor Györke; Przemysław B Radwański
Journal:  J Physiol       Date:  2017-03-26       Impact factor: 5.182

3.  Sodium and calcium regulation in cardiac myocytes: from molecules to heart failure and arrhythmia.

Authors:  Donald M Bers; Ye Chen-Izu
Journal:  J Physiol       Date:  2015-03-15       Impact factor: 5.182

4.  K+ channels and cardiac electrophysiology.

Authors:  Donald M Bers; Ye Chen-Izu
Journal:  J Physiol       Date:  2017-04-01       Impact factor: 5.182

5.  Shared and unique aspects of ligand- and voltage-gated ion-channel gating.

Authors:  Derek Bowie
Journal:  J Physiol       Date:  2018-05-15       Impact factor: 5.182

6.  Brugada syndrome trafficking-defective Nav1.5 channels can trap cardiac Kir2.1/2.2 channels.

Authors:  Marta Pérez-Hernández; Marcos Matamoros; Silvia Alfayate; Paloma Nieto-Marín; Raquel G Utrilla; David Tinaquero; Raquel de Andrés; Teresa Crespo; Daniela Ponce-Balbuena; B Cicero Willis; Eric N Jiménez-Vazquez; Guadalupe Guerrero-Serna; Andre M da Rocha; Katherine Campbell; Todd J Herron; F Javier Díez-Guerra; Juan Tamargo; José Jalife; Ricardo Caballero; Eva Delpón
Journal:  JCI Insight       Date:  2018-09-20

7.  Mutant SOD1 protein increases Nav1.3 channel excitability.

Authors:  Elif Kubat Öktem; Karen Mruk; Joshua Chang; Ata Akin; William R Kobertz; Robert H Brown
Journal:  J Biol Phys       Date:  2016-04-12       Impact factor: 1.365

8.  Cardiac Na Channels: Structure to Function.

Authors:  K R DeMarco; C E Clancy
Journal:  Curr Top Membr       Date:  2016-06-14       Impact factor: 3.049

Review 9.  Dysfunctional Nav1.5 channels due to SCN5A mutations.

Authors:  Dan Han; Hui Tan; Chaofeng Sun; Guoliang Li
Journal:  Exp Biol Med (Maywood)       Date:  2018-05-27

Review 10.  The cardiac sodium channel gene SCN5A and its gene product NaV1.5: Role in physiology and pathophysiology.

Authors:  Christiaan C Veerman; Arthur A M Wilde; Elisabeth M Lodder
Journal:  Gene       Date:  2015-09-08       Impact factor: 3.688

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