| Literature DB >> 25772040 |
Reindert Sleven1, Ellen Lanckacker1, Gaëlle Boulet1, Peter Delputte1, Louis Maes1, Paul Cos2.
Abstract
A novel in vitro onychomycosis model was developed to easily predict the topical activity potential of novel antifungal drugs. The model encompasses drug activity and diffusion through bovine hoof slices in a single experimental set-up. Results correspond well with the antifungal susceptibility assay and Franz cell diffusion test.Entities:
Keywords: Drug evaluation; Onychomycosis; Topical antifungals
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Year: 2015 PMID： 25772040 DOI： 10.1016/j.mimet.2015.03.009
Source DB: PubMed Journal: J Microbiol Methods ISSN： 0167-7012 Impact factor: 2.363