Literature DB >> 25771412

Hypoxia as a cause of treatment failure in non-small cell carcinoma of the lung.

Odd Terje Brustugun1.   

Abstract

Hypoxia is an important factor in tumor biology and is both a predictive and a prognostic factor in non-small cell lung cancer. The negative effect of low oxygenation on radiation therapy effect has been known for decades, but more recent research has emphasized that hypoxia also has a profound effect on a tumor's aggression and metastatic propensity. In this review, current knowledge on both these aspects of treatment failure in NSCLC due to hypoxia has been discussed, along with a presentation of modern methods for hypoxia measurement and current therapeutical interventions to circumvent the negative effect of hypoxia on treatment results.
Copyright © 2015 Elsevier Inc. All rights reserved.

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Year:  2014        PMID： 25771412     DOI： 10.1016/j.semradonc.2014.11.006

Source DB:  PubMed          Journal:  Semin Radiat Oncol        ISSN： 1053-4296            Impact factor:   5.934


  14 in total

1.  Dosimetry study of 18F-FMISO + PET/CT hypoxia imaging guidance on intensity-modulated radiation therapy for non-small cell lung cancer.

Authors:  H Li; D Xu; X Han; Q Ruan; X Zhang; Y Mi; M Dong; S Guo; Y Lin; B Wang; G Li
Journal:  Clin Transl Oncol       Date:  2018-04-05       Impact factor: 3.405

2.  Intrinsic Differences in Spatiotemporal Organization and Stromal Cell Interactions Between Isogenic Lung Cancer Cells of Epithelial and Mesenchymal Phenotypes Revealed by High-Dimensional Single-Cell Analysis of Heterotypic 3D Spheroid Models.

Authors:  Maria L Lotsberg; Gro V Røsland; Austin J Rayford; Sissel E Dyrstad; Camilla T Ekanger; Ning Lu; Kirstine Frantz; Linda E B Stuhr; Henrik J Ditzel; Jean Paul Thiery; Lars A Akslen; James B Lorens; Agnete S T Engelsen
Journal:  Front Oncol       Date:  2022-04-22       Impact factor: 5.738

Review 3.  The Use of Quantitative Imaging in Radiation Oncology: A Quantitative Imaging Network (QIN) Perspective.

Authors:  Robert H Press; Hui-Kuo G Shu; Hyunsuk Shim; James M Mountz; Brenda F Kurland; Richard L Wahl; Ella F Jones; Nola M Hylton; Elizabeth R Gerstner; Robert J Nordstrom; Lori Henderson; Karen A Kurdziel; Bhadrasain Vikram; Michael A Jacobs; Matthias Holdhoff; Edward Taylor; David A Jaffray; Lawrence H Schwartz; David A Mankoff; Paul E Kinahan; Hannah M Linden; Philippe Lambin; Thomas J Dilling; Daniel L Rubin; Lubomir Hadjiiski; John M Buatti
Journal:  Int J Radiat Oncol Biol Phys       Date:  2018-06-30       Impact factor: 7.038

4.  A novel approach to target hypoxic cancer cells via combining β-oxidation inhibitor etomoxir with radiation.

Authors:  Arpit Dheeraj; Chapla Agarwal; Isabel R Schlaepfer; David Raben; Rana Singh; Rajesh Agarwal; Gagan Deep
Journal:  Hypoxia (Auckl)       Date:  2018-08-21

5.  Alternatively Expressed Transcripts Analysis of Non-Small Cell Lung Cancer Cells under Different Hypoxic Microenvironment.

Authors:  Shunjun Wang; HuSai Ma; Huayang Li; Quan Liu; Suiqing Huang; Lin Huang; Li Luo; Yupeng Jiang; Zhongkai Wu
Journal:  J Oncol       Date:  2021-04-10       Impact factor: 4.375

6.  Kinomic profile in patient-derived glioma cells during hypoxia reveals c-MET-PI3K dependency for adaptation.

Authors:  Hong Sheng Cheng; Charlie Marvalim; Pengcheng Zhu; Cheng Lui Daniel Law; Zhi Yan Jeremy Low; Yuk Kien Chong; Beng Ti Ang; Carol Tang; Nguan Soon Tan
Journal:  Theranostics       Date:  2021-03-05       Impact factor: 11.556

Review 7.  Low temperature plasmas as emerging cancer therapeutics: the state of play and thoughts for the future.

Authors:  Adam M Hirst; Fiona M Frame; Manit Arya; Norman J Maitland; Deborah O'Connell
Journal:  Tumour Biol       Date:  2016-02-18

8.  LRIG1 acts as a critical regulator of melanoma cell invasion, migration, and vasculogenic mimicry upon hypoxia by regulating EGFR/ERK-triggered epithelial-mesenchymal transition.

Authors:  Wei Li; Yubo Zhou
Journal:  Biosci Rep       Date:  2019-01-08       Impact factor: 3.840

9.  HIF-1α and HIF-2α Differently Regulate the Radiation Sensitivity of NSCLC Cells.

Authors:  Eloy Moreno Roig; Arjan J Groot; Ala Yaromina; Tessa C Hendrickx; Lydie M O Barbeau; Lorena Giuranno; Glenn Dams; Jonathan Ient; Veronica Olivo Pimentel; Marike W van Gisbergen; Ludwig J Dubois; Marc A Vooijs
Journal:  Cells       Date:  2019-01-12       Impact factor: 6.600

10.  Long Distance From Microvessel to Cancer Cell Predicts Poor Prognosis in Non-Small Cell Lung Cancer Patients.

Authors:  Haiying Ding; Jiao Sun; Yu Song; Wenxiu Xin; Junfeng Zhu; Like Zhong; Yinbo Chen; Yiwen Zhang; Yinghui Tong; Luo Fang
Journal:  Front Oncol       Date:  2021-06-11       Impact factor: 6.244
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