Aude Fleurier1, Cecile Pelatan2, Stephanie Willot3, Jean-Louis Ginies4, Estelle Breton5, Laure Bridoux1, Jean-Francois Segura6, Emilie Chaillou4, Agathe Jobert7, Estelle Darviot4, Benoit Cagnard8, Nadege Delaperriere6, Isabelle Grimal9, Emilie Carre1, Anne-Claire Wagner7, Emmanuelle Sylvestre10, Alain Dabadie11. 1. CHU Rennes, Paediatric Centre, Hôpital Sud, Rennes Cedex, France. 2. CH Le Mans, Paediatric Department, Le Mans, France. 3. CHU Tours, Paediatric Department, CH Clocheville, Tours Cedex, France. 4. CHU Angers, Paediatric Department, Angers Cedex 01, France. 5. CH Saint Brieuc, Hôpital Y. Le Foll, Paediatric Department, Saint Brieuc, France. 6. CHU Brest, CH Morvan, Paediatric Department, Brest, France. 7. CH Saint Nazaire, Paediatric Department, Boulevard de l'hôpital, Saint Nazaire, France. 8. CH Auray-Vannes, Hôpital Bretagne Atlantique, Paediatric Department, Boulevard du Général Guillaudot, Vannes Cedex, France. 9. CH Cholet, Paediatric Department, Cholet Cedex, France. 10. CHU Rennes, Public Health Department, Rennes, France. 11. CHU Rennes, Paediatric Centre, Hôpital Sud, Rennes Cedex, France. Electronic address: Alain.dabadie@chu-rennes.fr.
Abstract
BACKGROUND: Children with inflammatory bowel disease are at risk of vaccine-preventable diseases mostly due to immunosuppressive drugs. AIM: To evaluate coverage after an awareness campaign informing patients, their parents and general practitioner about the vaccination schedule. METHODS: Vaccination coverage was firstly evaluated and followed by an awareness campaign on the risk of infection via postal mail. The trial is a case-control study on the same patients before and after the awareness campaign. Overall, 92 children were included. A questionnaire was then completed during a routine appointment to collect data including age at diagnosis, age at data collection, treatment history, and vaccination status. RESULTS: Vaccination rates significantly increased for vaccines against diphtheria-tetanus-poliomyelitis (92% vs. 100%), Haemophilus influenzae (88% vs. 98%), hepatitis B (52% vs. 71%), pneumococcus (36% vs. 57%), and meningococcus C (17% vs. 41%) (p<0.05). Children who were older at diagnosis were 1.26 times more likely to be up-to-date with a minimum vaccination schedule (diphtheria-tetanus-poliomyelitis, pertussis, H. influenzae, measles-mumps-rubella, tuberculosis) (p=0.002). CONCLUSION: Informing inflammatory bowel disease patients, their parents and general practitioner about the vaccination schedule via postal mail is easy, inexpensive, reproducible, and increases vaccination coverage. This method reinforces information on the risk of infection during routine visits.
BACKGROUND:Children with inflammatory bowel disease are at risk of vaccine-preventable diseases mostly due to immunosuppressive drugs. AIM: To evaluate coverage after an awareness campaign informing patients, their parents and general practitioner about the vaccination schedule. METHODS: Vaccination coverage was firstly evaluated and followed by an awareness campaign on the risk of infection via postal mail. The trial is a case-control study on the same patients before and after the awareness campaign. Overall, 92 children were included. A questionnaire was then completed during a routine appointment to collect data including age at diagnosis, age at data collection, treatment history, and vaccination status. RESULTS: Vaccination rates significantly increased for vaccines against diphtheria-tetanus-poliomyelitis (92% vs. 100%), Haemophilus influenzae (88% vs. 98%), hepatitis B (52% vs. 71%), pneumococcus (36% vs. 57%), and meningococcus C (17% vs. 41%) (p<0.05). Children who were older at diagnosis were 1.26 times more likely to be up-to-date with a minimum vaccination schedule (diphtheria-tetanus-poliomyelitis, pertussis, H. influenzae, measles-mumps-rubella, tuberculosis) (p=0.002). CONCLUSION: Informing inflammatory bowel diseasepatients, their parents and general practitioner about the vaccination schedule via postal mail is easy, inexpensive, reproducible, and increases vaccination coverage. This method reinforces information on the risk of infection during routine visits.