Literature DB >> 25769314

Parkinson's disease and enhanced inflammatory response.

Iva Stojkovska1, Brandon M Wagner1, Brad E Morrison2.   

Abstract

Parkinson's disease (PD) is the first and second most prevalent motor and neurodegenerative disease, respectively. The clinical symptoms of PD result from a loss of midbrain dopaminergic (DA) neurons. However, the molecular cause of DA neuron loss remains elusive. Mounting evidence implicates enhanced inflammatory response in the development and progression of PD pathology. This review examines current research connecting PD and inflammatory response.
© 2015 by the Society for Experimental Biology and Medicine.

Entities:  

Keywords:  Parkinson’s disease; disease models; inflammation; neuroinflammation

Mesh：

Substances：

Year:  2015        PMID： 25769314      PMCID： PMC4935292          DOI： 10.1177/1535370215576313

Source DB:  PubMed          Journal:  Exp Biol Med (Maywood)        ISSN： 1535-3699


  115 in total

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Journal:  Free Radic Biol Med       Date:  2012-06-09       Impact factor: 7.376

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Authors:  Y He; S Appel; W Le
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3.  Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease.

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4.  Head injury and Parkinson's disease risk in twins.

Authors:  Samuel M Goldman; Caroline M Tanner; David Oakes; Grace S Bhudhikanok; Anjali Gupta; J William Langston
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5.  Intrastriatal GDNF gene transfer by inducible lentivirus vectors protects dopaminergic neurons in a rat model of parkinsonism.

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Journal:  Exp Neurol       Date:  2014-07-02       Impact factor: 5.330

Review 6.  Paraquat and Parkinson's disease.

Authors:  C Berry; C La Vecchia; P Nicotera
Journal:  Cell Death Differ       Date:  2010-01-22       Impact factor: 15.828

7.  Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene.

Authors:  A Poltorak; X He; I Smirnova; M Y Liu; C Van Huffel; X Du; D Birdwell; E Alejos; M Silva; C Galanos; M Freudenberg; P Ricciardi-Castagnoli; B Layton; B Beutler
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8.  Intrastriatal lipopolysaccharide injection induces parkinsonism in C57/B6 mice.

Authors:  Randy L Hunter; Baohua Cheng; Dong-Young Choi; Mei Liu; Shuwei Liu; Wayne A Cass; Guoying Bing
Journal:  J Neurosci Res       Date:  2009-06       Impact factor: 4.164

9.  DJ-1 is a redox-dependent molecular chaperone that inhibits alpha-synuclein aggregate formation.

Authors:  Shoshana Shendelman; Alan Jonason; Cecile Martinat; Thomas Leete; Asa Abeliovich
Journal:  PLoS Biol       Date:  2004-10-05       Impact factor: 8.029

Review 10.  Cytokines and chemokines at the crossroads of neuroinflammation, neurodegeneration, and neuropathic pain.

Authors:  Geeta Ramesh; Andrew G MacLean; Mario T Philipp
Journal:  Mediators Inflamm       Date:  2013-08-12       Impact factor: 4.711
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  41 in total

1.  Maternal Hypermethioninemia Affects Neurons Number, Neurotrophins Levels, Energy Metabolism, and Na+,K+-ATPase Expression/Content in Brain of Rat Offspring.

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Journal:  Mol Neurobiol       Date:  2017-01-13       Impact factor: 5.590

2.  Parkin clearance of dysfunctional mitochondria regulates ROS levels and increases survival of human chondrocytes.

Authors:  M Y Ansari; N M Khan; I Ahmad; T M Haqqi
Journal:  Osteoarthritis Cartilage       Date:  2017-08-08       Impact factor: 6.576

Review 3.  Environmental neurotoxicant-induced dopaminergic neurodegeneration: a potential link to impaired neuroinflammatory mechanisms.

Authors:  Arthi Kanthasamy; Huajun Jin; Adhithiya Charli; Anantharam Vellareddy; Anumantha Kanthasamy
Journal:  Pharmacol Ther       Date:  2019-01-22       Impact factor: 12.310

4.  Influence of intranasal exposure of MPTP in multiple doses on liver functions and transition from non-motor to motor symptoms in a rat PD model.

Authors:  Indrani Datta; S R Mekha; Alka Kaushal; Kavina Ganapathy; Rema Razdan
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2019-08-29       Impact factor: 3.000

5.  Spinal cord injury and Parkinson's disease: a population-based, propensity score-matched, longitudinal follow-up study.

Authors:  T-S Yeh; Y-P Huang; H-I Wang; S-L Pan
Journal:  Spinal Cord       Date:  2016-05-31       Impact factor: 2.772

6.  Association of polymorphisms in the MCP-1 and CCR2 genes with the risk of Parkinson's disease.

Authors:  Yan Wang; Minhua Zhou; Yong Wang; Deqi Jiang; Xun Deng
Journal:  J Neural Transm (Vienna)       Date:  2019-08-30       Impact factor: 3.575

7.  Soluble Epoxide Hydrolase Inhibition Attenuates MPTP-Induced Neurotoxicity in the Nigrostriatal Dopaminergic System: Involvement of α-Synuclein Aggregation and ER Stress.

Authors:  Hui-Ju Huang; Yi-Ting Wang; Hui-Ching Lin; Yi-Hsuan Lee; Anya Maan-Yuh Lin
Journal:  Mol Neurobiol       Date:  2018-01       Impact factor: 5.590

8.  Succinobucol, a Non-Statin Hypocholesterolemic Drug, Prevents Premotor Symptoms and Nigrostriatal Neurodegeneration in an Experimental Model of Parkinson's Disease.

Authors:  Danúbia Bonfanti Santos; Dirleise Colle; Eduardo Luiz Gasnhar Moreira; Mariana Appel Hort; Marcelo Godoi; Gael Le Douaron; Antonio Luiz Braga; Jamil Assreuy; Patrick Pierre Michel; Rui Daniel Prediger; Rita Raisman-Vozari; Marcelo Farina
Journal:  Mol Neurobiol       Date:  2016-02-06       Impact factor: 5.590

9.  Low-Grade Inflammation Aggravates Rotenone Neurotoxicity and Disrupts Circadian Clock Gene Expression in Rats.

Authors:  Huan Li; Sheng Song; Yuan Wang; Chun Huang; Feng Zhang; Jie Liu; Jau-Shyong Hong
Journal:  Neurotox Res       Date:  2018-10-17       Impact factor: 3.911

10.  Mast Cells Release Chemokine CCL2 in Response to Parkinsonian Toxin 1-Methyl-4-Phenyl-Pyridinium (MPP(+)).

Authors:  Duraisamy Kempuraj; Ramasamy Thangavel; Ranan Fattal; Sagar Pattani; Evert Yang; Smita Zaheer; Donna A Santillan; Mark K Santillan; Asgar Zaheer
Journal:  Neurochem Res       Date:  2015-12-08       Impact factor: 3.996
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