Literature DB >> 2576915

A requirement for low concentration of hepatic glutathione for induction of gammaglutamyltransferase by phenobarbitone.

S A Braide1.   

Abstract

The effect of low concentration of hepatic glutathione on the induction of GGT by phenobarbitone was investigated. Rats were treated with diethyl maleate to decrease the hepatic concentration of GGT and with cysteine to increase glutathione concentration in the liver. All animals were then treated with phenobarbitone. The study shows that the induction of GGT is promoted by low concentration of hepatic glutathione.

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Year:  1989        PMID: 2576915

Source DB:  PubMed          Journal:  J Environ Pathol Toxicol Oncol        ISSN: 0731-8898            Impact factor:   3.567


  1 in total

1.  Associations between total serum GGT activity and metabolic risk: MESA.

Authors:  Ryan Bradley; Annette L Fitzpatrick; Nancy S Jenny; Duk-Hee Lee; David R Jacobs
Journal:  Biomark Med       Date:  2013-10       Impact factor: 2.851

  1 in total

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