Deepa Dash1, Teenu Mary Sebastian1, Meena Aggarwal1, Manjari Tripathi2. 1. All India Institute of Medical Sciences, Delhi, India. 2. Department of Neurology, All India Institute of Medical Sciences, Delhi, India. Electronic address: manjari.tripathi1@gmail.com.
Abstract
PURPOSE: This study was conducted to observe the effect of a structured educational program on drug adherence and self-care management in people with epilepsy in a developing country. METHODS: A total of 180 consecutive people with epilepsy were enrolled from the epilepsy clinic of a tertiary care hospital in North India. Out of these, 90 were randomized to the epilepsy health education group and received the educational program and 90 were in the control group and received the standard of care but did not receive any structured educational program. The modified Morisky Medication Adherence Scale (MMAS) and Epilepsy Self-Efficacy Scale (ESES) were administered to assess drug adherence and self-care, respectively, on the day of enrollment. The patients enrolled in the epilepsy health education group received4 sessions of the structured educational program. The MMAS and ESES questionnaires were again administered to both groups after 6months. STATISTICAL METHODS: Continuous and categorical variables were compared between control and epilepsy health education groups using a chi-square test, with p value less than 0.05 considered significant. A comparison between pretest and posttest MMAS scores and ESES scores was done using a paired t-test. RESULTS: In the epilepsy health education group, the pretest mean MMAS score was 6.58 whereas the posttest mean MMAS score was 7.53; the difference was significant (p=0.001). The mean MMAS scores for the control group's pretest and posttest were 6.46 and 6.58, respectively, which were not significantly different (p=0.224). On comparing the ESES scores at the beginning of the study and after 6months, there was no significant change in both groups. CONCLUSIONS: The present study proves the efficacy of a structured educational program in improving drug adherence in a cohort of people with epilepsy with low educational background.
RCT Entities:
PURPOSE: This study was conducted to observe the effect of a structured educational program on drug adherence and self-care management in people with epilepsy in a developing country. METHODS: A total of 180 consecutive people with epilepsy were enrolled from the epilepsy clinic of a tertiary care hospital in North India. Out of these, 90 were randomized to the epilepsy health education group and received the educational program and 90 were in the control group and received the standard of care but did not receive any structured educational program. The modified Morisky Medication Adherence Scale (MMAS) and Epilepsy Self-Efficacy Scale (ESES) were administered to assess drug adherence and self-care, respectively, on the day of enrollment. The patients enrolled in the epilepsy health education group received 4 sessions of the structured educational program. The MMAS and ESES questionnaires were again administered to both groups after 6months. STATISTICAL METHODS: Continuous and categorical variables were compared between control and epilepsy health education groups using a chi-square test, with p value less than 0.05 considered significant. A comparison between pretest and posttest MMAS scores and ESES scores was done using a paired t-test. RESULTS: In the epilepsy health education group, the pretest mean MMAS score was 6.58 whereas the posttest mean MMAS score was 7.53; the difference was significant (p=0.001). The mean MMAS scores for the control group's pretest and posttest were 6.46 and 6.58, respectively, which were not significantly different (p=0.224). On comparing the ESES scores at the beginning of the study and after 6months, there was no significant change in both groups. CONCLUSIONS: The present study proves the efficacy of a structured educational program in improving drug adherence in a cohort of people with epilepsy with low educational background.
Authors: Rosa Michaelis; Venus Tang; Sarah J Nevitt; Janelle L Wagner; Avani C Modi; William Curt LaFrance; Laura H Goldstein; Milena Gandy; Rebecca Bresnahan; Kette Valente; Kirsten A Donald; Markus Reuber Journal: Cochrane Database Syst Rev Date: 2020-09-07
Authors: Rosa Michaelis; Venus Tang; Janelle L Wagner; Avani C Modi; William Curt LaFrance; Laura H Goldstein; Tobias Lundgren; Markus Reuber Journal: Cochrane Database Syst Rev Date: 2017-10-27
Authors: Kelly L Hayward; Patricia C Valery; W Neil Cottrell; Katharine M Irvine; Leigh U Horsfall; Caroline J Tallis; Veronique S Chachay; Brittany J Ruffin; Jennifer H Martin; Elizabeth E Powell Journal: BMC Gastroenterol Date: 2016-09-13 Impact factor: 3.067