Literature DB >> 25768235

Modeling alternate RNA structures in genomic sequences.

Azadeh Saffarian1, Mathieu Giraud, Hélène Touzet.   

Abstract

We introduce the concept of RNA multistructures, which is a formal grammar-based framework specifically designed to model a set of alternate RNA secondary structures. Such alternate structures can either be a set of suboptimal foldings, or distinct stable folding states, or variants within an RNA family. We provide several such examples and propose an efficient algorithm to search for RNA multistructures within a genomic sequence.

Keywords:  RNA; algorithms; alignment; dynamic programming; secondary structure

Mesh:

Substances:

Year:  2015        PMID: 25768235     DOI: 10.1089/cmb.2014.0272

Source DB:  PubMed          Journal:  J Comput Biol        ISSN: 1066-5277            Impact factor:   1.479


  2 in total

1.  Structural prediction of RNA switches using conditional base-pair probabilities.

Authors:  Amirhossein Manzourolajdad; John L Spouge
Journal:  PLoS One       Date:  2019-06-12       Impact factor: 3.240

2.  Intrinsic Properties of tRNA Molecules as Deciphered via Bayesian Network and Distribution Divergence Analysis.

Authors:  Sergio Branciamore; Grigoriy Gogoshin; Massimo Di Giulio; Andrei S Rodin
Journal:  Life (Basel)       Date:  2018-02-08
  2 in total

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