Literature DB >> 2576797

Measurement of the relative binding affinity of zearalenone, alpha-zearalenol and beta-zearalenol for uterine and oviduct estrogen receptors in swine, rats and chickens: an indicator of estrogenic potencies.

D W Fitzpatrick1, C A Picken, L C Murphy, M M Buhr.   

Abstract

1. The relative binding affinity of zearalenone, alpha-zearalenol, and beta-zearalenol for estrogen receptors was determined in the pig, rat and chicken. 2. Similar relative binding patterns were observed, with alpha-zearalenol exhibiting greater affinity than zearalenone and beta-zearalenol the least binding affinity in all species. 3. The relative binding affinity of alpha-zearalenol was greater in pig, than in rat and significantly greater than in chicken. 4. Interspecies differences in zearalenone sensitivity may be due to the binding affinity of alpha-zearalenol for estrogen receptors and differences in zearalenone metabolites formed.

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Year:  1989        PMID： 2576797     DOI： 10.1016/0742-8413(89)90133-3

Source DB:  PubMed          Journal:  Comp Biochem Physiol C        ISSN： 0742-8413


  18 in total

1.  [Not Available].

Authors:  S Leitner; A Bucher; J Böhm; C Rosenkranz
Journal:  Mycotoxin Res       Date:  2001-03       Impact factor: 3.833

2.  Toxic effects of maternal zearalenone exposure on uterine capacity and fetal development in gestation rats.

Authors:  Yuanyuan Zhang; Zhiqiang Jia; Shutong Yin; Anshan Shan; Rui Gao; Zhe Qu; Min Liu; Shaoping Nie
Journal:  Reprod Sci       Date:  2013-12-19       Impact factor: 3.060

3.  Hydroxysteroid dehydrogenases in bovine and porcine granulosa cells convert zearalenone into its hydroxylated metabolites alpha-zearalenol and beta-zearalenol.

Authors:  H Malekinejad; B Colenbrander; J Fink-Gremmels
Journal:  Vet Res Commun       Date:  2006-05       Impact factor: 2.459

4.  E-Screen evaluation of sugar beet feedstuffs in a case of reduced embryo transfer efficiencies in cattle: the role of phytoestrogens and zearalenone.

Authors:  N W Shappell; M S Mostrom; E M Lenneman
Journal:  In Vitro Cell Dev Biol Anim       Date:  2012-02-21       Impact factor: 2.416

5.  Zearalenone-induced lymphophagocytosis (T cell apoptosis) on the rat's thymus.

Authors:  Mirsad Dorić; Svjetlana Radović; Mirsad Babić; Suada Kuskunović; Ivana Tomić; Ivan Selak
Journal:  Bosn J Basic Med Sci       Date:  2007-02       Impact factor: 3.363

6.  Functional pathology of the ovaries and uteri of premature female piglets exposed to distinct amounts of zearalenone.

Authors:  A Reischauer; C Ellenberger; S Döll; S Dänicke; S Dhein; U Schnurrbusch; H-A Schoon
Journal:  Mycotoxin Res       Date:  2005-06       Impact factor: 3.833

7.  Search for Hsp90 inhibitors with potential anticancer activity: isolation and SAR studies of radicicol and monocillin I from two plant-associated fungi of the Sonoran desert.

Authors:  Thomas J Turbyville; E M Kithsiri Wijeratne; Manping X Liu; Anna M Burns; Christopher J Seliga; Libia A Luevano; Cynthia L David; Stanley H Faeth; Luke Whitesell; A A Leslie Gunatilaka
Journal:  J Nat Prod       Date:  2006-02       Impact factor: 4.050

8.  Metabolism of zearalenone in the course of beer fermentation.

Authors:  Kohei Mizutani; Yasushi Nagatomi; Naoki Mochizuki
Journal:  Toxins (Basel)       Date:  2011-02-14       Impact factor: 4.546

9.  Examination of the estrogenicity of 2,4,6,2',6'-pentachlorobiphenyl (PCB 104), its hydroxylated metabolite 2,4,6,2',6'-pentachloro-4-biphenylol (HO-PCB 104), and a further chlorinated derivative, 2,4,6,2',4',6'-hexachlorobiphenyl (PCB 155).

Authors:  M R Fielden; I Chen; B Chittim; S H Safe; T R Zacharewski
Journal:  Environ Health Perspect       Date:  1997-11       Impact factor: 9.031

10.  A new zearalenone biodegradation strategy using non-pathogenic Rhodococcus pyridinivorans K408 strain.

Authors:  Rókus Kriszt; Csilla Krifaton; Sándor Szoboszlay; Mátyás Cserháti; Balázs Kriszt; József Kukolya; Arpád Czéh; Szilvia Fehér-Tóth; Lívia Török; Zsuzsanna Szőke; Krisztina J Kovács; Teréz Barna; Szilamér Ferenczi
Journal:  PLoS One       Date:  2012-09-25       Impact factor: 3.240
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