Cheng-Yu Lin1,2,3, Tung-Sheng Shih4,5, Saou-Hsing Liou6, Ming-Hsiu Lin5, Cheng-Ping Chang7, Tzu-Chieh Chou8,9. 1. Department of Otolaryngology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. 2. Department of Environmental and Occupational Health, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. 3. Department of Otolaryngology, Tainan Hospital, Ministry of Health and Welfare, Tainan, Taiwan. 4. Department of Occupational Safety and Health, College of Public Health, China Medical University, Taichung, Taiwan. 5. Institute of Labor, Occupational Safety and Health, Ministry of Labor, Executive Yuan, New Taipei, Taiwan. 6. Division of Environmental Health and Occupational Medicine, National Health Research Institutes, Miaoli, Taiwan. 7. Department of Occupational Safety and Health, Chang Jung Christian University, Tainan, Taiwan. 8. Department of Public Health, College of Public Health, China Medical University, Taichung, Taiwan. 9. Department of Health Risk Management, College of Public Health, China Medical University, Taichung, Taiwan.
Abstract
STUDY OBJECTIVES: Sleep-disordered breathing (SDB) is associated with an increased risk of motor vehicle crashes. This study aimed to understand SDB progression and related factors among professional drivers. METHODS: A total of 524 professional male drivers from a transportation company were included in this study. These drivers completed overnight in-home pulse oximetry studies both in 2006 and in 2009. Participants with abnormal results (oxygen desaturation index [ODI] ≥ 10 events/h) comprised the SDB group. Data included questionnaire information on demographics, medical history, SDB symptoms, and anthropometric measurements. RESULTS: A total of 318 male workers were recruited for further analysis. Fifty of these workers belonged to the SDB group. Workers with untreated SDB significantly progressed to a more severe state after three years. Baseline body mass index (BMI), baseline ODI, and change in BMI were all significant positive predictors of SDB progression (β = 0.823, 0.242, and 1.626; p = 0.047, 0.013, and 0.004, respectively). Compared with non-SDB drivers, SDB subjects showed a greater proportion of newly diagnosed cardiovascular disease (38.0%) at follow-up. CONCLUSIONS: Untreated SDB was a gradually progressive disorder in professional drivers over a three-year period. Subjects with high BMI and moderate to severe SDB should be closely monitored to allow for early detection of worsening SDB. Weight control should be highlighted in the management of SDB. COMMENTARY: A commentary on this article appears in this issue on page 409.
STUDY OBJECTIVES:Sleep-disordered breathing (SDB) is associated with an increased risk of motor vehicle crashes. This study aimed to understand SDB progression and related factors among professional drivers. METHODS: A total of 524 professional male drivers from a transportation company were included in this study. These drivers completed overnight in-home pulse oximetry studies both in 2006 and in 2009. Participants with abnormal results (oxygen desaturation index [ODI] ≥ 10 events/h) comprised the SDB group. Data included questionnaire information on demographics, medical history, SDB symptoms, and anthropometric measurements. RESULTS: A total of 318 male workers were recruited for further analysis. Fifty of these workers belonged to the SDB group. Workers with untreated SDB significantly progressed to a more severe state after three years. Baseline body mass index (BMI), baseline ODI, and change in BMI were all significant positive predictors of SDB progression (β = 0.823, 0.242, and 1.626; p = 0.047, 0.013, and 0.004, respectively). Compared with non-SDB drivers, SDB subjects showed a greater proportion of newly diagnosed cardiovascular disease (38.0%) at follow-up. CONCLUSIONS: Untreated SDB was a gradually progressive disorder in professional drivers over a three-year period. Subjects with high BMI and moderate to severe SDB should be closely monitored to allow for early detection of worsening SDB. Weight control should be highlighted in the management of SDB. COMMENTARY: A commentary on this article appears in this issue on page 409.
Authors: Eduardo H R Santos; Marco Tulio de Mello; Marcia Pradella-Hallinan; Ligia Luchesi; Maria Laura Nogueira Pires; Sergio Tufik Journal: Chronobiol Int Date: 2004 Impact factor: 2.877
Authors: Tuomas Karhu; Sami Myllymaa; Sami Nikkonen; Diego R Mazzotti; Juha Töyräs; Timo Leppänen Journal: Front Neurosci Date: 2021-04-28 Impact factor: 4.677