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Literature DB >> 25766287

RIG-I works double duty.

Abstract

The pathogen sensor RIG-I recognizes viral RNA and signals to induce an antiviral response. In this issue of Cell Host & Microbe, Weber et al. (2015), along with recent work by Sato et al. (2015), demonstrate that RIG-I directly inhibits viral replication independent of antiviral signaling.

Entities: Chemical Disease Gene Mutation Species

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Year: 2015 PMID： 25766287 PMCID： PMC5072393 DOI： 10.1016/j.chom.2015.02.014

Source DB: PubMed Journal: Cell Host Microbe ISSN： 1931-3128 Impact factor: 21.023

Keyword Cloud
References

10 in total

1. Introduction of virulence markers in PB2 of pandemic swine-origin influenza virus does not result in enhanced virulence or transmission.

Authors: Sander Herfst; Salin Chutinimitkul; Jianqiang Ye; Emmie de Wit; Vincent J Munster; Eefje J A Schrauwen; Theo M Bestebroer; Marcel Jonges; Adam Meijer; Marion Koopmans; Guus F Rimmelzwaan; Albert D M E Osterhaus; Daniel R Perez; Ron A M Fouchier
Journal: J Virol Date: 2010-02-03 Impact factor: 5.103

Review 2. Influenza A viruses: new research developments.

Authors: Rafael A Medina; Adolfo García-Sastre
Journal: Nat Rev Microbiol Date: 2011-07-11 Impact factor: 60.633

3. RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates.

Authors: Andreas Pichlmair; Oliver Schulz; Choon Ping Tan; Tanja I Näslund; Peter Liljeström; Friedemann Weber; Caetano Reis e Sousa
Journal: Science Date: 2006-10-12 Impact factor: 47.728

4. The RNA sensor RIG-I dually functions as an innate sensor and direct antiviral factor for hepatitis B virus.

Authors: Seiichi Sato; Kai Li; Takeshi Kameyama; Takaya Hayashi; Yuji Ishida; Shuko Murakami; Tsunamasa Watanabe; Sayuki Iijima; Yu Sakurai; Koichi Watashi; Susumu Tsutsumi; Yusuke Sato; Hidetaka Akita; Takaji Wakita; Charles M Rice; Hideyoshi Harashima; Michinori Kohara; Yasuhito Tanaka; Akinori Takaoka
Journal: Immunity Date: 2014-12-18 Impact factor: 31.745

5. Molecular basis for high virulence of Hong Kong H5N1 influenza A viruses.

Authors: M Hatta; P Gao; P Halfmann; Y Kawaoka
Journal: Science Date: 2001-09-07 Impact factor: 47.728

6. Influenza virus adaptation PB2-627K modulates nucleocapsid inhibition by the pathogen sensor RIG-I.

Authors: Michaela Weber; Hanna Sediri; Ulrike Felgenhauer; Ina Binzen; Sebastian Bänfer; Ralf Jacob; Linda Brunotte; Adolfo García-Sastre; Jonathan L Schmid-Burgk; Tobias Schmidt; Veit Hornung; Georg Kochs; Martin Schwemmle; Hans-Dieter Klenk; Friedemann Weber
Journal: Cell Host Microbe Date: 2015-02-19 Impact factor: 21.023

RIG-I works double duty.

1. Introduction of virulence markers in PB2 of pandemic swine-origin influenza virus does not result in enhanced virulence or transmission.

Review 2. Influenza A viruses: new research developments.

3. RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates.

4. The RNA sensor RIG-I dually functions as an innate sensor and direct antiviral factor for hepatitis B virus.

5. Molecular basis for high virulence of Hong Kong H5N1 influenza A viruses.

6. Influenza virus adaptation PB2-627K modulates nucleocapsid inhibition by the pathogen sensor RIG-I.

7. Hepatitis B virus infection.

8. Diverse intracellular pathogens activate type III interferon expression from peroxisomes.

Review 9. RIG-I-like receptor regulation in virus infection and immunity.

10. Species-specific inhibition of RIG-I ubiquitination and IFN induction by the influenza A virus NS1 protein.