BACKGROUND: Persistent erythema and severe rosacea flushing can cause significant physical discomfort and emotional stress to patients. Currently, no satisfactory treatments are available. METHODS: We report two cases of refractory flushing and erythema of rosacea that were successfully treated with intradermal botulinum toxin injections. RESULTS: Good cosmetic results were achieved for both patients. The side effects during and after treatment were mild pain and localized bruising; these symptoms resolved within several days without further treatment. CONCLUSION: Intradermal botulinum toxin injection may be an effective treatment for refractory erythema and rosacea flushing that deserves further study in a larger patient population.
BACKGROUND: Persistent erythema and severe rosacea flushing can cause significant physical discomfort and emotional stress to patients. Currently, no satisfactory treatments are available. METHODS: We report two cases of refractory flushing and erythema of rosacea that were successfully treated with intradermal botulinum toxin injections. RESULTS: Good cosmetic results were achieved for both patients. The side effects during and after treatment were mild pain and localized bruising; these symptoms resolved within several days without further treatment. CONCLUSION: Intradermal botulinum toxin injection may be an effective treatment for refractory erythema and rosacea flushing that deserves further study in a larger patient population.
Authors: Kui Young Park; Hyun Jung Kwon; Jae Min Kim; Guk Jin Jeong; Beom Joon Kim; Seong Jun Seo; Myeong Nam Kim Journal: Ann Dermatol Date: 2018-10-26 Impact factor: 1.444
Authors: Jie Zhu; Xi Ji; Min Li; Xiao-e Chen; Juan Liu; Jia-an Zhang; Dan Luo; Bing-rong Zhou Journal: Biomed Res Int Date: 2016-02-22 Impact factor: 3.411