Anindya Bhattacharya1, Yan Cui1. 1. Department of Microbiology, Immunology and Biochemistry and Center for Integrative and Translational Genomics, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Abstract
UNLABELLED: miR2GO is a web-based platform for comparative analyses of human miRNA functions. It includes two programs: miRmut2GO and miRpair2GO. miRmut2GO implements a knowledge-based method to assess the functional effects of genetic and somatic mutations in microRNA seed regions. The functional effects of a mutation are analysed by semantic comparison of enriched gene ontology (GO) annotations of the target gene sets for the wild-type and mutated alleles. miRpair2GO compares the functions of two different miRNAs based on the enriched functional annotations of their target gene sets. AVAILABILITY AND IMPLEMENTATION: The miR2GO web server is available at http://compbio.uthsc.edu/miR2GO.
UNLABELLED: miR2GO is a web-based platform for comparative analyses of human miRNA functions. It includes two programs: miRmut2GO and miRpair2GO. miRmut2GO implements a knowledge-based method to assess the functional effects of genetic and somatic mutations in microRNA seed regions. The functional effects of a mutation are analysed by semantic comparison of enriched gene ontology (GO) annotations of the target gene sets for the wild-type and mutated alleles. miRpair2GO compares the functions of two different miRNAs based on the enriched functional annotations of their target gene sets. AVAILABILITY AND IMPLEMENTATION: The miR2GO web server is available at http://compbio.uthsc.edu/miR2GO.
Authors: Tanvir Alam; Mahmut Uludag; Magbubah Essack; Adil Salhi; Haitham Ashoor; John B Hanks; Craig Kapfer; Katsuhiko Mineta; Takashi Gojobori; Vladimir B Bajic Journal: Nucleic Acids Res Date: 2017-03-17 Impact factor: 16.971
Authors: Eman A Toraih; Manal S Fawzy; Eman A Mohammed; Mohammad H Hussein; Mohamad M El-Labban Journal: Mol Diagn Ther Date: 2016-12 Impact factor: 4.074