Literature DB >> 25760427

Medical versus surgical management for emphysematous pancreatic necrosis: is gas within pancreatic necrosis an absolute indication for surgery?

Luis Barreda1, Javier Targarona, Elizabeth Pando, Miguel Reynel, Jose Portugal, Claudia Barreda.   

Abstract

OBJECTIVES: The aim of this study was to evaluate whether pancreatic necrosis with presence of gas is an absolute indication for surgery or if there is a possibility for the medical management of this pathology.
METHODS: This study is a retrospective study including 56 patients with diagnosis of pancreatic necrosis and gas on computed tomography from April 2003 to March 2011. We recorded all the factors related to each group of treatment, including APACHE II score, C-reactive protein level, Tomographic Severity Index, organ and multiorgan failure, and infected necrosis after fine-needle puncture, to evaluate the differences between surgical and medical treatment.
RESULTS: Thirty-six (64%) of these patients were submitted to surgery, whereas 20 (36%) were managed conservatively. Twenty-eight patients (78%) who underwent surgery had infected necrosis. Thirty-five percent of the patients (7 patients) in the medical group had organ failure versus 83% of the patients in the surgical group.
CONCLUSIONS: Pancreatic necrosis with gas on computed tomography is a relative indication for surgery. Medical management is a feasible and safe possibility for this pathology in selected cases. The presence of organ failure and infected necrosis often precludes a surgical treatment.

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Year:  2015        PMID: 25760427     DOI: 10.1097/MPA.0000000000000322

Source DB:  PubMed          Journal:  Pancreas        ISSN: 0885-3177            Impact factor:   3.327


  3 in total

1.  Emphysematous pancreatitis associated with penetrating duodenal ulcer.

Authors:  Claudio Tana; Mauro Silingardi; Maria Adele Giamberardino; Francesco Cipollone; Tiziana Meschi; Cosima Schiavone
Journal:  World J Gastroenterol       Date:  2017-12-28       Impact factor: 5.742

Review 2.  Open necrosectomy is feasible as a last resort in selected cases with infected pancreatic necrosis: a case series and systematic literature review.

Authors:  Lucia Ilaria Sgaramella; Angela Gurrado; Alessandro Pasculli; Francesco Paolo Prete; Fausto Catena; Mario Testini
Journal:  World J Emerg Surg       Date:  2020-07-29       Impact factor: 5.469

3.  Risk factors for mortality in emphysematous pancreatitis.

Authors:  Chin-Yao Chou; Yu-Jang Su; Hsiu-Wu Yang; Chen-Wang Chang
Journal:  J Drug Assess       Date:  2019-10-23
  3 in total

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