Literature DB >> 25759786

Atypical diabetic ketoacidosis: case report.

Hüseyin Demirci1, Ramazan Coşar2, Özcan Çiftçi3, Işılay Kalan Sarı3.   

Abstract

BACKGROUND: Diabetic ketoacidosis (DKA) is a potentially life-threatening complication of diabetes mellitus and can lead to death if untreated. It is a complex metabolic state characterised by hyperglycaemia, acidosis and ketonuria. Bonsai is one of the herbal incense products that contains synthetic cannabinoid and can be easily accessible via the internet in many countries. It cannot be detected in blood and urine studies using conventional methods. Synthetic cannabinoid abuse is associated with severe side effects, including tachycardia, high blood pressure, acidosis, excess sedation and coma. CASE REPORT: A 17-year-old male patient was brought to the emergency department with sudden onset of dyspnoea. Laboratory investigations revealed hyperglycaemia, acidosis and ketonuria. He was admitted to the intensive care unit with a diagnosis of diabetic ketoacidosis. He was not considered a typical case of diabetic ketoacidosis because of the tendency to hypokalaemia, persistent tachycardia and bronchoscopic findings. We learned from his friends that he had used cannabis for a week and used bonzai on the day that he was brought to the emergency service.
CONCLUSION: Diabetic ketoacidosis with prolonged acidosis and tendency to hypokalaemia are investigated for the consumption of synthetic cannabinoids.

Entities:  

Keywords:  Cannabinoids; diabetic ketoacidosis; hypokalaemia

Year:  2015        PMID: 25759786      PMCID: PMC4342127          DOI: 10.5152/balkanmedj.2015.15123

Source DB:  PubMed          Journal:  Balkan Med J        ISSN: 2146-3123            Impact factor:   2.021


  9 in total

1.  Synthetic cannabinoid exposures reported to Texas poison centers.

Authors:  Mathias B Forrester; Kurt Kleinschmidt; Evan Schwarz; Amy Young
Journal:  J Addict Dis       Date:  2011-10

2.  Acute intoxication by synthetic cannabinoids--four case reports.

Authors:  Maren Hermanns-Clausen; Stefan Kneisel; Melanie Hutter; Bela Szabo; Volker Auwärter
Journal:  Drug Test Anal       Date:  2013-05-20       Impact factor: 3.345

3.  The emergence and analysis of synthetic cannabinoids.

Authors:  Simon Hudson; John Ramsey
Journal:  Drug Test Anal       Date:  2011-02-21       Impact factor: 3.345

4.  Structure characterisation of urinary metabolites of the cannabimimetic JWH-018 using chemically synthesised reference material for the support of LC-MS/MS-based drug testing.

Authors:  Simon Beuck; Ines Möller; Andreas Thomas; Annika Klose; Nils Schlörer; Wilhelm Schänzer; Mario Thevis
Journal:  Anal Bioanal Chem       Date:  2011-04-01       Impact factor: 4.142

5.  Three cases of "spice" exposure.

Authors:  Joshua Simmons; Laura Cookman; Christopher Kang; Carl Skinner
Journal:  Clin Toxicol (Phila)       Date:  2011-06       Impact factor: 4.467

Review 6.  Marijuana-based drugs: innovative therapeutics or designer drugs of abuse?

Authors:  Kathryn A Seely; Paul L Prather; Laura P James; Jeffery H Moran
Journal:  Mol Interv       Date:  2011-02

Review 7.  The endocannabinoid system: physiology and pharmacology.

Authors:  Fernando Rodríguez de Fonseca; Ignacio Del Arco; Francisco Javier Bermudez-Silva; Ainhoa Bilbao; Andrea Cippitelli; Miguel Navarro
Journal:  Alcohol Alcohol       Date:  2004-11-18       Impact factor: 2.826

Review 8.  Hyperglycemic crises in adult patients with diabetes.

Authors:  Abbas E Kitabchi; Guillermo E Umpierrez; John M Miles; Joseph N Fisher
Journal:  Diabetes Care       Date:  2009-07       Impact factor: 17.152

9.  Beyond THC: The New Generation of Cannabinoid Designer Drugs.

Authors:  Liana Fattore; Walter Fratta
Journal:  Front Behav Neurosci       Date:  2011-09-21       Impact factor: 3.558

  9 in total
  1 in total

1.  Difficult-to-diagnose diabetes in a patient treated with cyclophosphamide - the contradictory roles of immunosuppressant agents: a case report.

Authors:  Manuel García-Sáenz; Daniel Uribe-Cortés; Claudia Ramírez-Rentería; Aldo Ferreira-Hermosillo
Journal:  J Med Case Rep       Date:  2018-12-10
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.