Literature DB >> 25759078

Delayed gastric emptying after pancreaticoduodenectomy. Risk factors, predictors of severity and outcome. A single center experience of 588 cases.

Ayman El Nakeeb1, Waleed Askr, Youssef Mahdy, Ahmed Elgawalby, Mohamed El Sorogy, Mostaffa Abu Zeied, Talaat Abdallah, Mohamed Abd Elwahab.   

Abstract

BACKGROUND: Delayed gastric emptying (DGE) is a common complication after pancreaticoduodenectomy (PD). This study was designed to evaluate perioperative risk variables for DGE after PD and analyze the factors that predict its severity. PATIENTS AND
METHOD: Demographic data, preoperative, intraoperative, and postoperative variables were collected.
RESULTS: A total of 588 consecutive patients underwent PD. One hundred and five patients (17.9 %) developed DGE of any type. Forty-three patients (7.3 %) had a type A, 53 patients (9.01 %) had DGE type B, and the remaining nine patients (1.5 %) had DGE type C. BMI > 25, diabetes mellitus (DM), preoperative biliary drainage, retrocolic reconstruction, type of pancreatic reconstruction, presence of complications, postoperative pancreatic fistula (POPF), and bile leaks were significantly associated with a higher incidence of DGE. Thirty-three (31.4 %) patients were diagnosed as primary DGE, while 72 (68.5 %) patients had DGE secondary to concomitant complications. Type B and C DGE were significantly noticed in secondary DGE (P = 0.04). Hospital stay was significantly shorter in primary DGE.
CONCLUSION: Retrocolic GJ, DM, presence of complications, type of pancreatic reconstruction, and severity of POPF were independent significant risk factors for development of DGE. Type B and C DGE were significantly more in secondary DGE.

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Year:  2015        PMID: 25759078     DOI: 10.1007/s11605-015-2795-2

Source DB:  PubMed          Journal:  J Gastrointest Surg        ISSN: 1091-255X            Impact factor:   3.452


  27 in total

1.  Factors influencing delayed gastric emptying after pylorus-preserving pancreatoduodenectomy.

Authors:  Yoon-Chan Park; Sun-Whe Kim; Jin-Young Jang; Young Joon Ahn; Yong-Hyun Park
Journal:  J Am Coll Surg       Date:  2003-06       Impact factor: 6.113

2.  Comprehensive analysis of variables affecting delayed gastric emptying following pancreaticoduodenectomy.

Authors:  John W Kunstman; Annabelle L Fonseca; Maria M Ciarleglio; Xiangyu Cong; Abby Hochberg; Ronald R Salem
Journal:  J Gastrointest Surg       Date:  2012-03-27       Impact factor: 3.452

3.  Delayed gastric emptying after pancreatoduodenectomy.

Authors:  Hiroshi Kurahara; Hiroyuki Shinchi; Kosei Maemura; Yuko Mataki; Satoshi Iino; Masahiko Sakoda; Shinichi Ueno; Sonshin Takao; Shoji Natsugoe
Journal:  J Surg Res       Date:  2011-08-26       Impact factor: 2.192

4.  Physiological hyperglycemia slows gastric emptying in normal subjects and patients with insulin-dependent diabetes mellitus.

Authors:  E Schvarcz; M Palmér; J Aman; M Horowitz; M Stridsberg; C Berne
Journal:  Gastroenterology       Date:  1997-07       Impact factor: 22.682

5.  Improvement of delayed gastric emptying in pylorus-preserving pancreaticoduodenectomy: results of a prospective, randomized, controlled trial.

Authors:  Masaji Tani; Hiroshi Terasawa; Manabu Kawai; Shinomi Ina; Seiko Hirono; Kazuhisa Uchiyama; Hiroki Yamaue
Journal:  Ann Surg       Date:  2006-03       Impact factor: 12.969

6.  Incidence of pancreatic anastomotic failure and delayed gastric emptying after pancreatoduodenectomy in 507 consecutive patients: use of a web-based calculator to improve homogeneity of definition.

Authors:  Yasushi Hashimoto; L William Traverso
Journal:  Surgery       Date:  2009-12-16       Impact factor: 3.982

7.  Ten-year experience with 733 pancreatic resections: changing indications, older patients, and decreasing length of hospitalization.

Authors:  J H Balcom; D W Rattner; A L Warshaw; Y Chang; C Fernandez-del Castillo
Journal:  Arch Surg       Date:  2001-04

8.  Braun enteroenterostomy is associated with reduced delayed gastric emptying and early resumption of oral feeding following pancreaticoduodenectomy.

Authors:  Steven N Hochwald; Stephen R Grobmyer; Alan W Hemming; Eleanor Curran; David A Bloom; Matthew Delano; Kevin E Behrns; Edward M Copeland; Stephen B Vogel
Journal:  J Surg Oncol       Date:  2010-04-01       Impact factor: 3.454

9.  Effect of antecolic or retrocolic reconstruction of the gastro/duodenojejunostomy on delayed gastric emptying after pancreaticoduodenectomy: a randomized controlled trial.

Authors:  Rajesh Gangavatiker; Sujoy Pal; Amit Javed; Nihar Ranjan Dash; Peush Sahni; Tushar Kanti Chattopadhyay
Journal:  J Gastrointest Surg       Date:  2011-03-16       Impact factor: 3.452

10.  Reconsideration of postoperative oral intake tolerance after pancreaticoduodenectomy: prospective consecutive analysis of delayed gastric emptying according to the ISGPS definition and the amount of dietary intake.

Authors:  Emi Akizuki; Yasutoshi Kimura; Takayuki Nobuoka; Masafumi Imamura; Minoru Nagayama; Tomoko Sonoda; Koichi Hirata
Journal:  Ann Surg       Date:  2009-06       Impact factor: 12.969

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  15 in total

1.  Reduction of the Incidence of Delayed Gastric Emptying in Side-to-Side Gastrojejunostomy in Subtotal Stomach-Preserving Pancreaticoduodenectomy.

Authors:  Toru Nakamura; Yoshiyasu Ambo; Takehiro Noji; Naoya Okada; Minoru Takada; Toru Shimizu; On Suzuki; Fumitaka Nakamura; Nobuichi Kashimura; Akihiro Kishida; Satoshi Hirano
Journal:  J Gastrointest Surg       Date:  2015-06-11       Impact factor: 3.452

Review 2.  Does the Ileal Brake Contribute to Delayed Gastric Emptying After Pancreatoduodenectomy?

Authors:  Savio G Barreto; John A Windsor
Journal:  Dig Dis Sci       Date:  2016-12-19       Impact factor: 3.199

3.  Clinical Efficacy of the Preservation of the Hepatic Branch of the Vagus Nerve on Delayed Gastric Emptying After Laparoscopic Pancreaticoduodenectomy.

Authors:  Xu Li; Tingting Qin; Feng Zhu; Min Wang; Chao Dang; Li He; Shutao Pan; Yuhui Liu; Taoyuan Yin; Yecheng Feng; Xin Wang; Yahong Yu; Ming Shen; Xingpei Lu; Yongjun Chen; Li Jiang; Chenjian Shi; Renyi Qin
Journal:  J Gastrointest Surg       Date:  2021-05-05       Impact factor: 3.452

4.  Contemporary Surgical, Oncological, and Survival Outcomes of Pancreaticoduodenectomy for Periampullary Tumours: a 5-Year Experience from Tertiary Cancer Center.

Authors:  Ravi Arjunan; S D S Karthik; Ramachandra Chowdappa; Syed Althaf; Chunduri Srinivas
Journal:  Indian J Surg Oncol       Date:  2021-08-16

5.  Afferent Loop Decompression Technique is Associated with a Reduction in Pancreatic Fistula Following Pancreaticoduodenectomy.

Authors:  Jie Yin; Zipeng Lu; Pengfei Wu; Junli Wu; Wentao Gao; Jishu Wei; Feng Guo; Jianmin Chen; Kuirong Jiang; Yi Miao
Journal:  World J Surg       Date:  2018-11       Impact factor: 3.352

6.  Impact of gastric resection and enteric anastomotic configuration on delayed gastric emptying after pancreaticoduodenectomy: a network meta-analysis of randomized trials.

Authors:  C Varghese; S Bhat; T H-H Wang; G O'Grady; S Pandanaboyana
Journal:  BJS Open       Date:  2021-05-07

Review 7.  Intestinal autotransplantation.

Authors:  Guosheng Wu
Journal:  Gastroenterol Rep (Oxf)       Date:  2017-07-17

8.  Superiority of stapled side-to-side gastrojejunostomy over conventional hand-sewn end-to-side gastrojejunostomy for reducing the risk of primary delayed gastric emptying after subtotal stomach-preserving pancreaticoduodenectomy.

Authors:  Yasuhiro Murata; Akihiro Tanemura; Hiroyuki Kato; Naohisa Kuriyama; Yoshinori Azumi; Masashi Kishiwada; Shugo Mizuno; Masanobu Usui; Hiroyuki Sakurai; Shuji Isaji
Journal:  Surg Today       Date:  2017-03-23       Impact factor: 2.549

9.  Trends and outcomes of pancreaticoduodenectomy for periampullary tumors: A 25-year single-center study of 1000 consecutive cases.

Authors:  Ayman El Nakeeb; Waleed Askar; Ehab Atef; Ehab El Hanafy; Ahmad M Sultan; Tarek Salah; Ahmed Shehta; Mohamed El Sorogy; Emad Hamdy; Mohamed El Hemly; Ahmed A El-Geidi; Tharwat Kandil; Mohamed El Shobari; Talaat Abd Allah; Amgad Fouad; Mostafa Abu Zeid; Ahmed Abu El Eneen; Nabil Gad El-Hak; Gamal El Ebidy; Omar Fathy; Ahmed Sultan; Mohamed Abdel Wahab
Journal:  World J Gastroenterol       Date:  2017-10-14       Impact factor: 5.742

Review 10.  Postoperative Complications, In-Hospital Mortality and 5-Year Survival After Surgical Resection for Patients with a Pancreatic Neuroendocrine Tumor: A Systematic Review.

Authors:  Anneke P J Jilesen; Casper H J van Eijck; K H in't Hof; S van Dieren; Dirk J Gouma; Els J M Nieveen van Dijkum
Journal:  World J Surg       Date:  2016-03       Impact factor: 3.352

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