Clarissa Pimentel de Souza 1 , Ronaldo Lucas 2 , Regina H R Ramadinha 3 , Tifanny B C P Pires 2 Show Affiliations »
Abstract
OBJECTIVES: We evaluated the efficacy of cryosurgery in association with itraconazole for the treatment of feline sporotrichosis. We also compared the length of treatment protocol with others reported in the literature. METHODS: Cats naturally infected with fungi of the Sporothrix schenckii complex were evaluated. Diagnosis was confirmed by cytology and fungal culture. Prior to the cryosurgical procedure, every animal was receiving itraconazole 10 mg/kg/day PO, for different time periods. The same protocol was maintained until 4 weeks after complete healing of the lesions. RESULTS: Eleven of 13 cats were considered clinically cured. The treatment duration ranged from 14-64 weeks (median 32 weeks). CONCLUSIONS AND RELEVANCE: The combination of cryosurgery and itraconazole was effective in treating cases of feline sporotrichosis and decreased the treatment length compared with protocols using only medication. © ISFM and AAFP 2015.
OBJECTIVES: We evaluated the efficacy of cryosurgery in association with itraconazole for the treatment of feline sporotrichosis. We also compared the length of treatment protocol with others reported in the literature. METHODS: Cats naturally infected with fungi of the Sporothrix schenckii complex were evaluated. Diagnosis was confirmed by cytology and fungal culture. Prior to the cryosurgical procedure, every animal was receiving itraconazole 10 mg/kg/day PO, for different time periods. The same protocol was maintained until 4 weeks after complete healing of the lesions. RESULTS: Eleven of 13 cats were considered clinically cured. The treatment duration ranged from 14-64 weeks (median 32 weeks). CONCLUSIONS AND RELEVANCE: The combination of cryosurgery and itraconazole was effective in treating cases of feline sporotrichosis and decreased the treatment length compared with protocols using only medication. © ISFM and AAFP 2015.
Entities: Chemical
Species
Mesh： See more »
Substances： See more »
Year: 2015
PMID： 25758667 DOI： 10.1177/1098612X15575777
Source DB: PubMed Journal: J Feline Med Surg ISSN： 1098-612X Impact factor: 2.015