| Literature DB >> 25756367 |
Hai-Xia Wu1,2, Lei Tan1, Zhao-Wen Tang1, Mei-Yan Yang1, Jian-Yun Xiao1, Chuan-Jun Liu1, Ren-Xi Zhuo1.
Abstract
This work presented a highly efficient antibacterial Ti-surface which was grafted with poly(N-hydroxyethylacrylamide) (PHEAA) brush and further decorated with triclosan (TCS). The modified surfaces were characterized using contact angle measurements, X-ray photoelectron spectroscopy, and attenuated total reflectance Fourier transform infrared. The antibacterial performance of the modified surfaces was evaluated using the Streptococcus mutans and Actinomyces naeslundii attachment test. The Ti surface with PHEAA brush (Ti-PHEAA) was able to resist the adhesion of the bacteria, while the TCS-decorated Ti surface (Ti-TCS) showed the capability of killing the bacteria adhered on the surface. As we coupled the TCS to the PHEAA brush, the surface showed highly efficient antibacterial performance due to the combination of the resistance to the bacteria adhesion and its activity of killing bacteria.Entities:
Keywords: antibacterial surface; poly(N-hydroxyethylacrylamide); polymer brush; resistance to bacterial adhesion; surface grafting; triclosan
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Year: 2015 PMID: 25756367 DOI: 10.1021/acsami.5b01210
Source DB: PubMed Journal: ACS Appl Mater Interfaces ISSN: 1944-8244 Impact factor: 9.229