Literature DB >> 25755603

Role of external beam radiation therapy in management of hepatocellular carcinoma.

Hanish Sharma1.   

Abstract

Diagnosis at advanced disease stage and early vascular invasion are the bane of majority of patients with hepatocellular carcinoma (HCC) in India. The currently standardized curative and palliative treatment modalities [surgery, ablative techniques, trans-catheter chemotherapy, systemic chemotherapy] are suboptimal for a significant proportion of disease stages. Interest in radiotherapy for hepatocellular carcinoma has seen a resurgence with revolutionary improvements in targeting radiation doses safely. Encouraging results have been reported with a host of radiation techniques from conformal radiotherapy, stereotactic whole body radiation therapy to charged particle based therapies. The dissemination of this knowledge has been slow across other specialties involved in care of patients with HCC. However the increasing availability of radiotherapy services predicts a hopeful future for wider evaluation of radiotherapy in HCC.

Entities:  

Keywords:  CRT, conformal radiotherapy; HCC, hepatocellular carcinoma; IGRT, image guided radiotherapy; RFA, radiofrequency ablation; RILD, radiation-induced liver disease; RT, radiotherapy; SBRT; SBRT, stereotactic body radiotherapy; proton beam therapy; radiation induced liver disease; radiotherapy in hepatocellular carcinoma

Year:  2014        PMID: 25755603      PMCID: PMC4284217          DOI: 10.1016/j.jceh.2014.05.002

Source DB:  PubMed          Journal:  J Clin Exp Hepatol        ISSN: 0973-6883


  35 in total

1.  Clinical results and risk factors of proton and carbon ion therapy for hepatocellular carcinoma.

Authors:  Shohei Komatsu; Takumi Fukumoto; Yusuke Demizu; Daisuke Miyawaki; Kazuki Terashima; Ryohei Sasaki; Yuichi Hori; Yoshio Hishikawa; Yonson Ku; Masao Murakami
Journal:  Cancer       Date:  2011-04-14       Impact factor: 6.860

2.  Clinical profile, etiology and therapeutic outcome in 324 hepatocellular carcinoma patients at a tertiary care center in India.

Authors:  Shashi B Paul; Sreenivasa Baba Chalamalasetty; Sreenivas Vishnubhatla; Kaushal Madan; Shivanand R Gamanagatti; Yogesh Batra; Siddhartha D Gupta; Subrat K Panda; Subrat K Acharya
Journal:  Oncology       Date:  2009-07-28       Impact factor: 2.935

3.  Escalated focal liver radiation and concurrent hepatic artery fluorodeoxyuridine for unresectable intrahepatic malignancies.

Authors:  L A Dawson; C J McGinn; D Normolle; R K Ten Haken; S Walker; W Ensminger; T S Lawrence
Journal:  J Clin Oncol       Date:  2000-06       Impact factor: 44.544

4.  60Co moving strip technique in the management of carcinoma of the ovary: analysis of tumor control and morbidity.

Authors:  C A Perez; A Korba; F Zivnuska; S Prasad; A L Katzenstein
Journal:  Int J Radiat Oncol Biol Phys       Date:  1978 May-Jun       Impact factor: 7.038

5.  Modeling of normal tissue response to radiation: the critical volume model.

Authors:  A Niemierko; M Goitein
Journal:  Int J Radiat Oncol Biol Phys       Date:  1993-01       Impact factor: 7.038

6.  The safety and efficacy of high-dose proton beam radiotherapy for hepatocellular carcinoma: a phase 2 prospective trial.

Authors:  David A Bush; Zeid Kayali; Roger Grove; Jerry D Slater
Journal:  Cancer       Date:  2011-01-24       Impact factor: 6.860

7.  Radiotherapy for painful bone metastases from hepatocellular carcinoma.

Authors:  Jinsil Seong; Woong Sup Koom; Hee Chul Park
Journal:  Liver Int       Date:  2005-04       Impact factor: 5.828

8.  Proton beam therapy for hepatocellular carcinoma: a retrospective review of 162 patients.

Authors:  Toshiya Chiba; Koichi Tokuuye; Yasushi Matsuzaki; Shinji Sugahara; Yoshimichi Chuganji; Kenji Kagei; Junichi Shoda; Masaharu Hata; Masato Abei; Hiroshi Igaki; Naomi Tanaka; Yasuyuki Akine
Journal:  Clin Cancer Res       Date:  2005-05-15       Impact factor: 12.531

9.  Radiotherapy for osseous metastases from hepatocellular carcinoma: a retrospective study of 57 patients.

Authors:  T Kaizu; K Karasawa; Y Tanaka; T Matuda; H Kurosaki; S Tanaka; T Kumazaki
Journal:  Am J Gastroenterol       Date:  1998-11       Impact factor: 10.864

10.  Combination chemotherapy and radiation for palliation of hepatocellular carcinoma.

Authors:  V Dhir; V S Swaroop; K M Mohandas; K A Dinshaw; D C Desai; A Nagral; V Sharma; P Jagannath; L J Desouza
Journal:  Am J Clin Oncol       Date:  1992-08       Impact factor: 2.339

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  7 in total

Review 1.  Molecular imaging and therapy targeting copper metabolism in hepatocellular carcinoma.

Authors:  Jason Wachsmann; Fangyu Peng
Journal:  World J Gastroenterol       Date:  2016-01-07       Impact factor: 5.742

Review 2.  New horizons in ablation therapy for hepatocellular carcinoma.

Authors:  Jacob Freedman; Henrik Nilsson; Eduard Jonas
Journal:  Hepat Oncol       Date:  2015-11-06

Review 3.  Management of liver cancer. The Surgeon's point of view.

Authors:  Pierre Rabinel; Damien Dousse; Fabrice Muscari; Bertrand Suc
Journal:  Rep Pract Oncol Radiother       Date:  2017-03-23

Review 4.  Pathology and images of radiation-induced hepatitis: a review article.

Authors:  Shigeyuki Takamatsu; Kazuto Kozaka; Satoshi Kobayashi; Norihide Yoneda; Kotaro Yoshida; Dai Inoue; Azusa Kitao; Takahiro Ogi; Tetsuya Minami; Wataru Kouda; Tomoyasu Kumano; Nobukazu Fuwa; Osamu Matsui; Toshifumi Gabata
Journal:  Jpn J Radiol       Date:  2018-03-05       Impact factor: 2.374

5.  Minimum absolute lymphocyte counts during radiation are associated with a worse prognosis in patients with unresectable hepatocellular carcinoma.

Authors:  Qianqian Zhao; Xiaoqing Xu; Jinbo Yue; Kunli Zhu; Rui Feng; Shumei Jiang; Zhonghua Qi; Renben Wang
Journal:  Therap Adv Gastroenterol       Date:  2016-12-29       Impact factor: 4.409

6.  Stattic Enhances Radiosensitivity and Reduces Radio-Induced Migration and Invasion in HCC Cell Lines through an Apoptosis Pathway.

Authors:  Gang Xu; Lihua Zhu; Yan Wang; Yawei Shi; Aihua Gong; Chaoyang Wu
Journal:  Biomed Res Int       Date:  2017-10-26       Impact factor: 3.411

Review 7.  Therapeutic Strategies in HCC: Radiation Modalities.

Authors:  R Gallicchio; A Nardelli; P Mainenti; A Nappi; D Capacchione; V Simeon; C Sirignano; F Abbruzzi; F Barbato; M Landriscina; G Storto
Journal:  Biomed Res Int       Date:  2016-08-03       Impact factor: 3.411

  7 in total

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