Literature DB >> 25755585

Potential newer therapeutic targets for hepatitis B virus drug development.

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Abstract

Entities:  

Keywords:  AP, apurinic/apyrimidinic; APOBEC3, apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3; DHBV, duck HBV; HBV, Hepatitis B virus; HCC, hepatocellular carcinoma; LTβR, lymphotoxin-β receptor; PHH, primary human hepatocytes; RC-DNA, relaxed circular DNA; TDP, tyrosyl-DNA-phosphodiesterase; ccc, covalently closed circular; dHEPSRG, differentiated HepaRG; pgRNA, pregenomic RNA

Year:  2014        PMID： 25755585      PMCID： PMC4298638          DOI： 10.1016/j.jceh.2014.11.001

Source DB:  PubMed          Journal:  J Clin Exp Hepatol        ISSN： 0973-6883


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  5 in total

1.  Extensive editing of both hepatitis B virus DNA strands by APOBEC3 cytidine deaminases in vitro and in vivo.

Authors:  Rodolphe Suspène; Denise Guétard; Michel Henry; Peter Sommer; Simon Wain-Hobson; Jean-Pierre Vartanian
Journal:  Proc Natl Acad Sci U S A       Date:  2005-05-26       Impact factor: 11.205

2.  Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA.

Authors:  Julie Lucifora; Yuchen Xia; Florian Reisinger; Ke Zhang; Daniela Stadler; Xiaoming Cheng; Martin F Sprinzl; Herwig Koppensteiner; Zuzanna Makowska; Tassilo Volz; Caroline Remouchamps; Wen-Min Chou; Wolfgang E Thasler; Norbert Hüser; David Durantel; T Jake Liang; Carsten Münk; Markus H Heim; Jeffrey L Browning; Emmanuel Dejardin; Maura Dandri; Michael Schindler; Mathias Heikenwalder; Ulrike Protzer
Journal:  Science       Date:  2014-02-20       Impact factor: 47.728

Review 3.  Current and future therapies for hepatitis C virus infection.

Authors:  T Jake Liang; Marc G Ghany
Journal:  N Engl J Med       Date:  2013-05-16       Impact factor: 91.245

4.  Long-term hepatitis B surface antigen (HBsAg) kinetics during nucleoside/nucleotide analogue therapy: finite treatment duration unlikely.

Authors:  Stéphane Chevaliez; Christophe Hézode; Stéphane Bahrami; Marion Grare; Jean-Michel Pawlotsky
Journal:  J Hepatol       Date:  2012-12-03       Impact factor: 25.083

5.  Involvement of the host DNA-repair enzyme TDP2 in formation of the covalently closed circular DNA persistence reservoir of hepatitis B viruses.

Authors:  Christian Königer; Ida Wingert; Moritz Marsmann; Christine Rösler; Jürgen Beck; Michael Nassal
Journal:  Proc Natl Acad Sci U S A       Date:  2014-09-08       Impact factor: 11.205
  5 in total

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