Literature DB >> 25755472

Living Donor Liver Transplant is a Transparent Activity in India.

Subash Gupta1.   

Abstract

Living donor liver transplant (LDLT) has progressed rapidly in India with at least two major centers performing over 200 transplants annually. There have been concerns regarding donor safety as donor deaths have been reported worldwide. In India, there is a possible underreporting of donor complications and mortality leading to the allegation that LDLT is a clandestine activity. Deceased donor liver transplantation activity may be less transparent as there are no national guidelines for retrieval and allocation of organs. LDLT is for a named person and as the activity can only be conducted in major hospitals with involvement of over 100 medical personnel in each operation, it cannot be a clandestine operation. Government regulations require licensing of hospitals following inspection by senior doctors and reporting of transplant activity periodically. About 2500 living donor liver transplants have been conducted in India and there have been 7 donor deaths reported in India. Rather than not being transparent, donor morbidity and mortality has received excessive media attention. Most liver transplant activity in India is well organized with clearance from hepatologists and anesthetists. Unrelated donation needs to be cleared from a State appointed Authorization Committee. Foreigners cannot be transplanted without State clearance and approval of the concerned embassy. The donor risk is discussed and the success of the recipient operation is also explained to all patients. The ever-increasing popularity of the operation in spite of the high cost and the requirement for donation from a family member suggests that many patients are living healthy life after transplantation. Overall LDLT is a transparent activity in India.

Entities:  

Keywords:  DDLT, deceased donar liver transplantation; HOTA, Human Organ Transplant Act; India; LDLT, living donor liver transplant; donor; liver transplant

Year:  2012        PMID: 25755472      PMCID: PMC3940100          DOI: 10.1016/j.jceh.2012.10.001

Source DB:  PubMed          Journal:  J Clin Exp Hepatol        ISSN: 0973-6883


  11 in total

1.  Hospital is fined for "woeful care": Mt. Sinai cited for deficiencies after liver donor's death.

Authors:  D Grady
Journal:  N Y Times Web       Date:  2002-03-13

2.  Early liver transplantation for severe alcoholic hepatitis.

Authors:  Philippe Mathurin; Christophe Moreno; Didier Samuel; Jérôme Dumortier; Julia Salleron; François Durand; Hélène Castel; Alain Duhamel; Georges-Philippe Pageaux; Vincent Leroy; Sébastien Dharancy; Alexandre Louvet; Emmanuel Boleslawski; Valerio Lucidi; Thierry Gustot; Claire Francoz; Christian Letoublon; Denis Castaing; Jacques Belghiti; Vincent Donckier; François-René Pruvot; Jean-Charles Duclos-Vallée
Journal:  N Engl J Med       Date:  2011-11-10       Impact factor: 91.245

Review 3.  Paid transplants in India: the grim reality.

Authors:  Vivekanand Jha
Journal:  Nephrol Dial Transplant       Date:  2004-03       Impact factor: 5.992

4.  Living donor liver transplantation.

Authors:  A V Srinivas
Journal:  Indian J Med Ethics       Date:  2005 Jul-Sep

5.  The enigmatic nature of altruism in organ transplantation: a cross-cultural study of transplant physicians' views on altruism.

Authors:  Marie-Chantal Fortin; Marianne Dion-Labrie; Marie-Josée Hébert; Hubert Doucet
Journal:  BMC Res Notes       Date:  2010-07-30

6.  Adult-to-adult Right Hepatic Lobe Living Donor Liver Transplantation.

Authors:  James F. Trotter
Journal:  Curr Treat Options Gastroenterol       Date:  2002-12

7.   Risk factors for in-hospital mortality of patients with high model for end-stage liver disease scores following living donor liver transplantation.

Authors:  Chuan Li; Tian-Fu Wen; Lu-Nan Yan; Bo Li; Jia-Ying Yang; Ming-Qing Xu; Wen-Tao Wang; Yong-Gang Wei
Journal:  Ann Hepatol       Date:  2012 Jul-Aug       Impact factor: 2.400

Review 8.  Is there an advantage of living over deceased donation in liver transplantation?

Authors:  Cristiano Quintini; Koji Hashimoto; Teresa Diago Uso; Charles Miller
Journal:  Transpl Int       Date:  2012-09-02       Impact factor: 3.782

9.  Liver transplant recipient survival benefit with living donation in the model for endstage liver disease allocation era.

Authors:  Carl L Berg; Robert M Merion; Tempie H Shearon; Kim M Olthoff; Robert S Brown; Talia B Baker; Gregory T Everson; Johnny C Hong; Norah Terrault; Paul H Hayashi; Robert A Fisher; James E Everhart
Journal:  Hepatology       Date:  2011-10       Impact factor: 17.425

10.  Extended criteria for living donor liver transplantation in patients with advanced hepatocellular carcinoma.

Authors:  H J Choi; D G Kim; G H Na; T H Hong; Y K You
Journal:  Transplant Proc       Date:  2012-03       Impact factor: 1.066

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  3 in total

Review 1.  Living donor liver transplantation in India.

Authors:  Gomathy Narasimhan
Journal:  Hepatobiliary Surg Nutr       Date:  2016-04       Impact factor: 7.293

2.  Diaphragmatic herniation following donor hepatectomy for living donor liver transplantation: a serious complication not given due recognition.

Authors:  Rajiv Lochan; Rehan Saif; Naveen Ganjoo; Mallikarjun Sakpal; Charles Panackal; Kaiser Raja; Jayanth Reddy; Sonal Asthana; Mathew Jacob
Journal:  Ann Hepatobiliary Pancreat Surg       Date:  2017-11-30

3.  Living Donor Liver Transplant in Patients Aged 60 Years or Older: Experience from a Large Volume Centre in India.

Authors:  Ravindra Nidoni; Rajasekhar Kandagaddala; Shaleen Agarwal; Rajesh Dey; Bhargava R Chikkala; Subhash Gupta
Journal:  J Clin Exp Hepatol       Date:  2020-07-18
  3 in total

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