| Literature DB >> 25755443 |
Shweta Singh1, Vaibhav Nasa1, Manish Tandon1.
Abstract
Liver transplant (LT) is a major surgical undertaking involving major fluid shifts, hemodynamic instability and metabolic derangements in a patient with preexisting liver failure and multisystemic derangements. Monitoring and organ support initiated in the preoperative phase is continued intraoperatively and into the postoperative phase to ensure an optimal outcome. As cardiovascular events are the leading cause of non-graft related death among LT recipients, major emphasis is placed on cardiovascular monitoring. The other essential monitoring are the continuous assessment of coagulapathy, extent of metabolic derangements, dyselectrolytemis and intracranial pressure monitoring in patients with fulminant hepatic failure. The type and extent of monitoring differs with need according to preexisting child status of the patient and the extent of systemic derangements. It also varies among transplant centers and is mainly determined by individual or institutional practices.Entities:
Keywords: ACT, activated clotting time; ALF; ALF, acute liver failure; APTT, activated partial thromboplastin time; ARDS, acute respiratory distress syndrome; CCO, continuous CO; CCTs, conventional coagulation tests; CI, cardiac index; CL, clot lysis; CO, cardiac output; CR, clot rate; CVP, central venous pressure; ESLD, end stage liver disease; EVLWI, extra vascular lung water index; ICG, indocyanine green; ICH, intracranial hypertension; ICP, intracranial pressure; LT, liver transplant; MA, maximum amplitude; ONSD, optic nerve sheath diameter; PAC, pulmonary artery catheter; PAOP, pulmonary arterial occlusion pressure; PF, platelet function; PI, pulsatility index; PT, prothrombin time; ROTEM, rotation thrombelastometry; RVEDV, right ventricular end-diastolic volume; SV, stroke volume; SVR, systemic vascular resistance; TCD, transcranial Doppler; TDCO, thermodilution principle; TEE, transesophageal echocardiography; TEG, thrombelastography; cirrhosis; coagulopathy; intracranial pressure monitoring; liver transplant; mPAP, mean pulmonary artery pressure
Year: 2012 PMID: 25755443 PMCID: PMC3940305 DOI: 10.1016/j.jceh.2012.06.003
Source DB: PubMed Journal: J Clin Exp Hepatol ISSN: 0973-6883