| Literature DB >> 25754991 |
Antonina Andreeva1, Dave Howorth1, Cyrus Chothia1, Eugene Kulesha2, Alexey G Murzin1.
Abstract
SCOP2 is a successor to the Structural Classification of Proteins (SCOP) database that organizes proteins of known structure according to their structural and evolutionary relationships. It was designed to provide a more advanced framework for the classification of proteins. The SCOP2 classification is described in terms of a directed acyclic graph in which each node defines a relationship of particular type that is represented by a region of protein structure and sequence. The SCOP2 data are accessible via SCOP2-Browser and SCOP2-Graph. This protocol unit describes different ways to explore and investigate the SCOP2 evolutionary and structural groupings.Entities:
Keywords: protein evolution; protein structure; sequence-structure relationship
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Year: 2015 PMID： 25754991 DOI： 10.1002/0471250953.bi0126s49
Source DB: PubMed Journal: Curr Protoc Bioinformatics ISSN： 1934-3396