| Literature DB >> 2575462 |
R Iemura, M Hori, T Saito, H Ohtaka.
Abstract
With the aim of obtaining new H1-antihistaminic agents, transformations of previously reported antihistaminic benzimidazoles were performed on the basis of the concept of bioisosterism. Among the compounds prepared, imidazo[4,5-b]pyridine (8) and 4(3H)-quinazolinone (11) exhibited significant H1-antihistaminic activity.Entities:
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Year: 1989 PMID： 2575462 DOI： 10.1248/cpb.37.2723
Source DB: PubMed Journal: Chem Pharm Bull (Tokyo) ISSN： 0009-2363 Impact factor: 1.645