Literature DB >> 25753103

A comparative study of Zingiber officinale Roscoe pulp and peel: phytochemical composition and evaluation of antitumour activity.

Mariangela Marrelli1, Francesco Menichini, Filomena Conforti.   

Abstract

Colon cancer is one of the major causes of cancer mortality worldwide. Hydroalcoholic extract of ginger peel extract was more potent against colon cancer cells than ginger pulp hydroalcoholic extract using MTT assay, while ginger pulp hydroalcoholic extract showed higher anti-inflammatory and antioxidant activities. The two samples of ginger showed a different polyphenolic content and lipophilic composition. Peel extract possessed twice the polyphenolic content than pulp and the highest number of non-polar compounds. Among them, α-zingibirene was found to be the major constituent. The findings add to epidemiologic evidence for therapeutic effects of ginger peel in colorectal carcinoma.

Entities:  

Keywords:  NO production; Zingiber officinale; colorectal carcinoma; fatty acids; phytosterols

Mesh：

Substances：

Year:  2015        PMID： 25753103     DOI： 10.1080/14786419.2015.1020491

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN： 1478-6419            Impact factor:   2.861


  9 in total

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Journal:  Int J Mol Sci       Date:  2018-02-28       Impact factor: 5.923

2.  Pharmacokinetics of 10-gingerol and 6-shogaol in the plasma of healthy subjects treated with red ginger (Zingiber officinale var. Rubrum) suspension.

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Review 3.  Gingers and Their Purified Components as Cancer Chemopreventative Agents.

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Journal:  Molecules       Date:  2019-08-07       Impact factor: 4.411

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6.  Assessment of Photo-Induced Cytotoxic Activity of Cachrys sicula and Cachrys libanotis Enriched-Coumarin Extracts against Human Melanoma Cells.

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7.  Integration of medicinal plants into the traditional system of medicine for the treatment of cancer in Sokoto State, Nigeria.

Authors:  Ibrahim Malami; Nasiru Muhammad Jagaba; Ibrahim Babangida Abubakar; Aliyu Muhammad; Alhassan Muhammad Alhassan; Peter Maitama Waziri; Ibrahim Zakiyya Yakubu Yahaya; Halilu Emmanuel Mshelia; Sylvester Nefy Mathias
Journal:  Heliyon       Date:  2020-09-02

8.  Phytochemical and Biological Profile of Moricandia arvensis (L.) DC.: An Inhibitor of Pancreatic Lipase.

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Review 9.  Medicinal Plants in the Prevention and Treatment of Colon Cancer.

Authors:  Paola Aiello; Maedeh Sharghi; Shabnam Malekpour Mansourkhani; Azam Pourabbasi Ardekan; Leila Jouybari; Nahid Daraei; Khadijeh Peiro; Sima Mohamadian; Mahdiyeh Rezaei; Mahdi Heidari; Ilaria Peluso; Fereshteh Ghorat; Anupam Bishayee; Wesam Kooti
Journal:  Oxid Med Cell Longev       Date:  2019-12-04       Impact factor: 6.543
  9 in total

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