Literature DB >> 25752948

Neuroinflammation: Targeting neuroinflammation through inhibition of NLRP3.

Alex Chase.   

Abstract

Entities:  

Year:  2015        PMID： 25752948     DOI： 10.1038/nrneurol.2015.31

Source DB:  PubMed          Journal:  Nat Rev Neurol        ISSN： 1759-4758            Impact factor:   42.937


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  2 in total

1.  The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease.

Authors:  Yun-Hee Youm; Kim Y Nguyen; Ryan W Grant; Emily L Goldberg; Monica Bodogai; Dongin Kim; Dominic D'Agostino; Noah Planavsky; Christopher Lupfer; Thirumala D Kanneganti; Seokwon Kang; Tamas L Horvath; Tarek M Fahmy; Peter A Crawford; Arya Biragyn; Emad Alnemri; Vishwa Deep Dixit
Journal:  Nat Med       Date:  2015-02-16       Impact factor: 53.440

2.  A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.

Authors:  Rebecca C Coll; Avril A B Robertson; Jae Jin Chae; Sarah C Higgins; Raúl Muñoz-Planillo; Marco C Inserra; Irina Vetter; Lara S Dungan; Brian G Monks; Andrea Stutz; Daniel E Croker; Mark S Butler; Moritz Haneklaus; Caroline E Sutton; Gabriel Núñez; Eicke Latz; Daniel L Kastner; Kingston H G Mills; Seth L Masters; Kate Schroder; Matthew A Cooper; Luke A J O'Neill
Journal:  Nat Med       Date:  2015-02-16       Impact factor: 53.440
  2 in total
  3 in total

1.  Tyrosine phosphatase SHP2 negatively regulates NLRP3 inflammasome activation via ANT1-dependent mitochondrial homeostasis.

Authors:  Wenjie Guo; Wen Liu; Zhen Chen; Yanhong Gu; Shuang Peng; Lihong Shen; Yan Shen; Xingqi Wang; Gen-Sheng Feng; Yang Sun; Qiang Xu
Journal:  Nat Commun       Date:  2017-12-18       Impact factor: 14.919

Review 2.  Cell Death Pathways: a Novel Therapeutic Approach for Neuroscientists.

Authors:  G Morris; A J Walker; M Berk; M Maes; B K Puri
Journal:  Mol Neurobiol       Date:  2017-10-19       Impact factor: 5.590

3.  Clemastine improves hypomyelination in rats with hypoxic-ischemic brain injury by reducing microglia-derived IL-1β via P38 signaling pathway.

Authors:  Di Xie; Xiaoli Ge; Yanli Ma; Jialong Tang; Yang Wang; Yajie Zhu; Chengjin Gao; Shuming Pan
Journal:  J Neuroinflammation       Date:  2020-02-15       Impact factor: 8.322
  3 in total

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