Literature DB >> 25750869

Determination of injection site in flexor digitorum longus for effective and safe botulinum toxin injection.

Hong Geum Kim1, Myung Eun Chung1, Dae Heon Song1, Ju Yong Kim1, Bo Mi Sul1, Chang Hoon Oh1, Nam Su Park1.   

Abstract

OBJECTIVE: To determine the optimal injection site in the flexor digitorum longus (FDL) muscle for effective botulinum toxin injection.
METHODS: Fourteen specimens from eight adult Korean cadavers were used in this study. The most proximal medial point of the tibia plateau was defined as the proximal reference point; the most distal tip of the medial malleolus was defined as the distal reference point. The distance of a line connecting the proximal and distal reference points was defined as the reference length. The X-coordinate was the distance from the proximal reference point to the intramuscular motor endpoint (IME), or motor entry point (MEP) on the reference line, and the Y-coordinate was the distance from the nearest point from MEP on the medial border of the tibia to the MEP. IME and MEP distances from the proximal reference point were evaluated using the raw value and the X-coordinate to reference length ratio was determined as a percentage.
RESULTS: The majority of IMEs were located within 30%-60% of the reference length from the proximal reference point. The majority of the MEPs were located within 40%-60% of the reference length from the proximal reference point.
CONCLUSION: We recommend the anatomical site for a botulinum toxin injection in the FDL to be within a region 30%-60% of the reference length from the proximal reference point.

Entities:  

Keywords:  Botulinum toxins; Claw toes; Flexor digitorum longus; Spasticity

Year:  2015        PMID: 25750869      PMCID: PMC4351492          DOI: 10.5535/arm.2015.39.1.32

Source DB:  PubMed          Journal:  Ann Rehabil Med        ISSN: 2234-0645


  38 in total

Review 1.  Targeting the neuromuscular junction in skeletal muscles.

Authors:  Martin K Childers
Journal:  Am J Phys Med Rehabil       Date:  2004-10       Impact factor: 2.159

2.  Effective zone of botulinum toxin a injections in hallux claw toe syndrome: an anatomical study.

Authors:  Je-Hun Lee; Seung-Ho Han; Jun-Feng Ye; Be-Na Lee; Xiaochun An; Seong-Oh Kwon
Journal:  Muscle Nerve       Date:  2012-02       Impact factor: 3.217

3.  Intramuscular nerve distribution pattern of the adductor longus and gracilis muscles demonstrated with Sihler staining: guidance for botulinum toxin injection.

Authors:  Sung-Yoon Won; Dong-Wook Rha; Hong-San Kim; Sang-Hoon Jung; Eun Sook Park; Kyung-Seok Hu; Hee-Jin Kim
Journal:  Muscle Nerve       Date:  2012-05-29       Impact factor: 3.217

4.  Localization of motor nerve branches of the human psoas muscle.

Authors:  Anja Van Campenhout; Guy Hubens; Katrien Fagard; Guy Molenaers
Journal:  Muscle Nerve       Date:  2010-08       Impact factor: 3.217

Review 5.  Injection techniques for botulinum toxin using electromyography and electrical stimulation.

Authors:  C F O'Brien
Journal:  Muscle Nerve Suppl       Date:  1997

6.  Anatomic localization of motor entry points and accurate regions for botulinum toxin injection in the flexor digitorum superficialis.

Authors:  J F Ye; J H Lee; X C An; C H Lin; B Yue; Seung-Ho Han
Journal:  Surg Radiol Anat       Date:  2011-01-22       Impact factor: 1.246

7.  Botulinum toxin-A injections for spastic toe clawing.

Authors:  Erle C H Lim; Benjamin K C Ong; Raymond C S Seet
Journal:  Parkinsonism Relat Disord       Date:  2005-09-29       Impact factor: 4.891

8.  Juvenile and adult rat neuromuscular junctions: density, distribution, and morphology.

Authors:  Jianjun Ma; Beth P Smith; Thomas L Smith; Francis O Walker; Eileen V Rosencrance; L Andrew Koman
Journal:  Muscle Nerve       Date:  2002-12       Impact factor: 3.217

9.  Quantifying the spread of botulinum toxin through muscle fascia.

Authors:  C M Shaari; E George; B L Wu; H F Biller; I Sanders
Journal:  Laryngoscope       Date:  1991-09       Impact factor: 3.325

10.  A randomised, double blind, placebo controlled trial of botulinum toxin in the treatment of spastic foot in hemiparetic patients.

Authors:  P Burbaud; L Wiart; J L Dubos; E Gaujard; X Debelleix; P A Joseph; J M Mazaux; B Bioulac; M Barat; A Lagueny
Journal:  J Neurol Neurosurg Psychiatry       Date:  1996-09       Impact factor: 10.154

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