Literature DB >> 25750164

Treatment changes following aberrant urine drug test results for patients prescribed chronic opioid therapy.

Benjamin J Morasco1, Erin E Krebs2, Renee Cavanagh3, Stephanie Hyde4, Aysha Crain5, Steven K Dobscha1.   

Abstract

BACKGROUND/
OBJECTIVE: Urine drug testing (UDT) may be used to help screen for prescription opioid misuse. There are little data available describing usual pain care practices for patients who have aberrant UDT results. The goal of this research was to evaluate the clinical care for patients prescribed chronic opioid therapy (COT) and have an aberrant UDT.
DESIGN: Retrospective cohort study.
SETTING: VA Medical Center in the Pacific Northwest. PARTICIPANTS: Patients with chronic pain who were prescribed COT and had a UDT result that was positive for an illicit or nonprescribed substance. MAIN OUTCOME MEASURES: This was an exploratory study designed to document usual care practices.
RESULTS: Participants' (n = 83) mean age was 49.5 (SD = 9.6) and 81.5 percent were male. The most common substances detected on UDT were marijuana (69 percent) or a nonprescribed opioid (25 percent); 18 percent had a UDT positive for two or more substances. Plans to modify treatment were documented in 69 percent of cases. The most common treatment change after aberrant UDT results was instituting more frequent UDTs, which occurred in 43 percent of cases. Clinicians documented plans to alter their opioid prescribing (eg, terminating opioids, requiring more frequent fills, changing opioid dose, or transitioning to another opioid) in 52 percent of cases, but implemented these changes in only 24 percent. DISCUSSION: Current methods for optimizing treatment after obtaining aberrant UDT results should be enhanced. To improve the utility of UDT to reduce prescription opioid misuse, additional interventions and support for clinicians need to be developed and tested.

Entities:  

Mesh:

Substances:

Year:  2015        PMID: 25750164     DOI: 10.5055/jom.2015.0251

Source DB:  PubMed          Journal:  J Opioid Manag        ISSN: 1551-7489


  6 in total

Review 1.  Review of the Current State of Urine Drug Testing in Chronic Pain: Still Effective as a Clinical Tool and Curbing Abuse, or an Arcane Test?

Authors:  Krishnan Chakravarthy; Aneesh Goel; George M Jeha; Alan David Kaye; Paul J Christo
Journal:  Curr Pain Headache Rep       Date:  2021-02-17

2.  Provider reasons for discontinuing long-term opioid therapy following aberrant urine drug tests differ based on the type of substance identified.

Authors:  Jessica J Wyse; Benjamin J Morasco; Steven K Dobscha; Michael I Demidenko; Thomas H A Meath; Travis I Lovejoy
Journal:  J Opioid Manag       Date:  2018 Jul/Aug

3.  Provider Misinterpretation, Documentation, and Follow-Up of Definitive Urine Drug Testing Results.

Authors:  Isaac Chua; Athena K Petrides; Gordon D Schiff; Jaime R Ransohoff; Michalis Kantartjis; Jocelyn Streid; Christiana A Demetriou; Stacy E F Melanson
Journal:  J Gen Intern Med       Date:  2019-11-11       Impact factor: 5.128

4.  Clinician Response to Aberrant Urine Drug Test Results of Patients Prescribed Opioid Therapy for Chronic Pain.

Authors:  Benjamin J Morasco; Erin E Krebs; Melissa H Adams; Stephanie Hyde; Janet Zamudio; Steven K Dobscha
Journal:  Clin J Pain       Date:  2019-01       Impact factor: 3.442

5.  Substance Use Disorder Treatment Following Clinician-Initiated Discontinuation of Long-Term Opioid Therapy Resulting from an Aberrant Urine Drug Test.

Authors:  Shannon M Nugent; Steven K Dobscha; Benjamin J Morasco; Michael I Demidenko; Thomas H A Meath; Joseph W Frank; Travis I Lovejoy
Journal:  J Gen Intern Med       Date:  2017-06-09       Impact factor: 5.128

6.  Management of problematic behaviours among individuals on long-term opioid therapy: protocol for a Delphi study.

Authors:  Jessica S Merlin; Sarah R Young; Soraya Azari; William C Becker; Jane M Liebschutz; Jamie Pomeranz; Payel Roy; Shalini Saini; Joanna L Starrels; E Jennifer Edelman
Journal:  BMJ Open       Date:  2016-05-06       Impact factor: 2.692

  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.