Literature DB >> 25749728

The effect of vertebral fracture on the early neurologic recovery in patients with central cord syndrome.

Gregory D Schroeder1, Christopher K Kepler, Nik Hjelm, Alexander R Vaccaro, Michael S Weinstein.   

Abstract

PURPOSE: To compare early changes in the ASIA Motor Score (AMS) between patients with central cord syndrome (CCS) from an acute fracture to patients without a fracture.
METHODS: Patients with CCS were identified and stratified based on the presence of a fracture. The AMS through the first week of the patients' hospitalization was obtained. Initial injury severity as well as early neurologic recovery was measured using the AMS. Analysis of variance was performed to determine if age, gender, rectal tone at presentation, congenital stenosis, or surgery within 24 h significantly effected the change in AMS.
RESULTS: A strong trend (p = 0.0504) towards a more severe initial neurologic injury in patients with a fracture (AMS 59.7) than in patients without a fracture (AMS 70.2) was identified. However, in the week after injury, patients with a fracture had an improvement in their neurologic function (ΔAMS +4.8) while patients without a fracture demonstrated neurologic decline (ΔAMS -5.9). The change in AMS between patients with and without a fracture was nearly significant (p = 0.06).
CONCLUSION: Patients with central cord syndrome present with similar symptoms, but injuries with and without a fracture may be associated with a different early neurologic recovery. Patients with a fracture have a more severe injury at initial presentation, but tend to have neurologic improvement in the first week; conversely patients without a fracture have a less severe initial neurologic injury, but tend to have a slight decline in neurologic function over the first week.

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Year:  2015        PMID: 25749728     DOI: 10.1007/s00586-015-3865-6

Source DB:  PubMed          Journal:  Eur Spine J        ISSN: 0940-6719            Impact factor:   3.134


  17 in total

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2.  Human neuropathological and animal model evidence supporting a role for Fas-mediated apoptosis and inflammation in cervical spondylotic myelopathy.

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3.  Agreement between orthopedic surgeons and neurosurgeons regarding a new algorithm for the treatment of thoracolumbar injuries: a multicenter reliability study.

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4.  Factors predicting motor recovery and functional outcome after traumatic central cord syndrome: a long-term follow-up.

Authors:  Marcel F Dvorak; Charles G Fisher; Joel Hoekema; Michael Boyd; Vanessa Noonan; Peter C Wing; Brian K Kwon; Brian Kwon
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5.  Predictors of neurologic recovery in acute central cervical cord injury with only upper extremity impairment.

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Journal:  Spine (Phila Pa 1976)       Date:  2002-08-01       Impact factor: 3.468

6.  Traumatic central cord syndrome: results of surgical management.

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7.  Traumatic central cord syndrome: neurologic recovery after surgical management.

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Review 8.  Pathophysiology and natural history of cervical spondylotic myelopathy.

Authors:  Spyridon K Karadimas; W Mark Erwin; Claire G Ely; Joseph R Dettori; Michael G Fehlings
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9.  Effectiveness of surgical treatment for traumatic central cord syndrome.

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Journal:  J Neurosurg Spine       Date:  2009-01

10.  A novel experimental model of cervical spondylotic myelopathy (CSM) to facilitate translational research.

Authors:  Spyridon K Karadimas; Eun Su Moon; Wen-Ru Yu; Kajana Satkunendrarajah; Joannis K Kallitsis; Georgios Gatzounis; Michael G Fehlings
Journal:  Neurobiol Dis       Date:  2013-03-04       Impact factor: 5.996

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  3 in total

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Journal:  Eur Spine J       Date:  2019-07-31       Impact factor: 3.134

2.  Clinical outcomes of late decompression surgery following cervical spinal cord injury with pre-existing cord compression.

Authors:  Tsunehiko Konomi; Akimasa Yasuda; Kanehiro Fujiyoshi; Junichi Yamane; Shinjiro Kaneko; Takatsugu Komiyama; Masakazu Takemitsu; Yoshiyuki Yato; Osahiko Tsuji; Morio Matsumoto; Masaya Nakamura; Takashi Asazuma
Journal:  Spinal Cord       Date:  2017-12-19       Impact factor: 2.772

3.  Management of Acute Traumatic Central Cord Syndrome: A Narrative Review.

Authors:  Srikanth N Divi; Gregory D Schroeder; John J Mangan; Madeline Tadley; Wyatt L Ramey; Jetan H Badhiwala; Michael G Fehlings; F Cumhur Oner; Frank Kandziora; Lorin M Benneker; Emiliano N Vialle; Shanmuganathan Rajasekaran; Jens R Chapman; Alexander R Vaccaro
Journal:  Global Spine J       Date:  2019-05-08
  3 in total

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