Literature DB >> 25749208

D-ß-hydroxybutyrate: an anti-aging ketone body.

Clare Edwards1, Neil Copes1, Patrick C Bradshaw1.   

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Year:  2015        PMID： 25749208      PMCID： PMC4414129          DOI： 10.18632/oncotarget.3423

Source DB:  PubMed          Journal:  Oncotarget        ISSN： 1949-2553


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  7 in total

1.  Dietary restriction suppresses proteotoxicity and enhances longevity by an hsf-1-dependent mechanism in Caenorhabditis elegans.

Authors:  Katherine A Steinkraus; Erica D Smith; Christina Davis; Daniel Carr; William R Pendergrass; George L Sutphin; Brian K Kennedy; Matt Kaeberlein
Journal:  Aging Cell       Date:  2008-03-10       Impact factor: 9.304

2.  The ERK-MAPK pathway regulates longevity through SKN-1 and insulin-like signaling in Caenorhabditis elegans.

Authors:  Tetsuya Okuyama; Hideki Inoue; Sadatsugu Ookuma; Takayuki Satoh; Kei Kano; Sakiko Honjoh; Naoki Hisamoto; Kunihiro Matsumoto; Eisuke Nishida
Journal:  J Biol Chem       Date:  2010-07-12       Impact factor: 5.157

Review 3.  Ketone bodies, potential therapeutic uses.

Authors:  R L Veech; B Chance; Y Kashiwaya; H A Lardy; G F Cahill
Journal:  IUBMB Life       Date:  2001-04       Impact factor: 3.885

4.  Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor.

Authors:  Tadahiro Shimazu; Matthew D Hirschey; John Newman; Wenjuan He; Kotaro Shirakawa; Natacha Le Moan; Carrie A Grueter; Hyungwook Lim; Laura R Saunders; Robert D Stevens; Christopher B Newgard; Robert V Farese; Rafael de Cabo; Scott Ulrich; Katerina Akassoglou; Eric Verdin
Journal:  Science       Date:  2012-12-06       Impact factor: 47.728

Review 5.  The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies.

Authors:  Marwan Maalouf; Jong M Rho; Mark P Mattson
Journal:  Brain Res Rev       Date:  2008-09-25

6.  Valproic acid extends Caenorhabditis elegans lifespan.

Authors:  Kimberley Evason; James J Collins; Cheng Huang; Stacie Hughes; Kerry Kornfeld
Journal:  Aging Cell       Date:  2008-01-29       Impact factor: 9.304

7.  D-beta-hydroxybutyrate extends lifespan in C. elegans.

Authors:  Clare Edwards; John Canfield; Neil Copes; Muhammad Rehan; David Lipps; Patrick C Bradshaw
Journal:  Aging (Albany NY)       Date:  2014-08       Impact factor: 5.682
  7 in total
  6 in total

Review 1.  Targeting metabolic pathways for extension of lifespan and healthspan across multiple species.

Authors:  Andrey A Parkhitko; Elizabeth Filine; Stephanie E Mohr; Alexey Moskalev; Norbert Perrimon
Journal:  Ageing Res Rev       Date:  2020-10-05       Impact factor: 11.788

Review 2.  The role of lipid metabolism in aging, lifespan regulation, and age-related disease.

Authors:  Adiv A Johnson; Alexandra Stolzing
Journal:  Aging Cell       Date:  2019-09-27       Impact factor: 9.304

3.  Metabolic Rewiring by Human Placenta-Derived Mesenchymal Stem Cell Therapy Promotes Rejuvenation in Aged Female Rats.

Authors:  Kyeoung-Hwa Kim; Kyung-Ah Lee
Journal:  Int J Mol Sci       Date:  2022-01-05       Impact factor: 5.923

4.  The ketone body β-hydroxybutyrate mitigates the senescence response of glomerular podocytes to diabetic insults.

Authors:  Yudong Fang; Bohan Chen; Athena Y Gong; Deepak K Malhotra; Rajesh Gupta; Lance D Dworkin; Rujun Gong
Journal:  Kidney Int       Date:  2021-07-08       Impact factor: 10.612

Review 5.  Beneficial Effects of Exogenous Ketogenic Supplements on Aging Processes and Age-Related Neurodegenerative Diseases.

Authors:  Zsolt Kovács; Brigitta Brunner; Csilla Ari
Journal:  Nutrients       Date:  2021-06-26       Impact factor: 5.717

Review 6.  Nutritional Ketosis and Mitohormesis: Potential Implications for Mitochondrial Function and Human Health.

Authors:  Vincent J Miller; Frederick A Villamena; Jeff S Volek
Journal:  J Nutr Metab       Date:  2018-02-11
  6 in total

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