Grace C Haser1, Henry K Su2, Michael J Pitman3, Azita S Khorsandi4. 1. Thyroid Head and Neck Cancer (THANC) Foundation, Mount Sinai Beth Israel, 10 Union Square East, Suite 5B, New York, NY, USA. Electronic address: ghaser@thancfoundation.org. 2. Thyroid Head and Neck Cancer (THANC) Foundation, Mount Sinai Beth Israel, 10 Union Square East, Suite 5B, New York, NY, USA. Electronic address: hsu@thancfoundation.org. 3. Department of Otolaryngology-Head and Neck Surgery, New York Eye and Ear Infirmary, 310 East 14th Street, New York, NY, USA. Electronic address: mpitman@nyee.edu. 4. Department of Radiology, Mount Sinai Beth Israel, 10 Union Square East, New York, NY, USA. Electronic address: akhorsan@chpnet.org.
Abstract
BACKGROUND: Extramedullary plasmacytoma is a rare plasma cell neoplasm of the soft tissues characterized by the presence of a single, discrete lesion without evidence of systemic disease. Extramedullary plasmacytoma may disseminate into multiple myeloma, a systemic plasma cell disease. METHODS: A rare case of extramedullary plasmacytoma of the cricoid cartilage with solitary plasmacytoma of the rib was reviewed. RESULTS: The patient was found to have two discrete lesions; one of the cricoid cartilage and one of the lateral left fifth rib. Despite the presence of multiple tumors, the patient was not diagnosed with multiple myeloma as the bone marrow appeared normal. CONCLUSIONS: Due to the rarity of these neoplasms and the unusual localization of the extramedullary plasmacytoma tumor, a definitive diagnosis was difficult to make in this case. This case may be instructive for the differential diagnosis of laryngeal lesions.
BACKGROUND: Extramedullary plasmacytoma is a rare plasma cell neoplasm of the soft tissues characterized by the presence of a single, discrete lesion without evidence of systemic disease. Extramedullary plasmacytoma may disseminate into multiple myeloma, a systemic plasma cell disease. METHODS: A rare case of extramedullary plasmacytoma of the cricoid cartilage with solitary plasmacytoma of the rib was reviewed. RESULTS: The patient was found to have two discrete lesions; one of the cricoid cartilage and one of the lateral left fifth rib. Despite the presence of multiple tumors, the patient was not diagnosed with multiple myeloma as the bone marrow appeared normal. CONCLUSIONS: Due to the rarity of these neoplasms and the unusual localization of the extramedullary plasmacytoma tumor, a definitive diagnosis was difficult to make in this case. This case may be instructive for the differential diagnosis of laryngeal lesions.
Authors: Elżbieta Szczepanek; Joanna Drozd-Sokołowska; Jacek Sokołowski; Anna Rzepakowska; Arkadiusz Moskwa; Jakub Pachla; Jakub Grzybowski; Katarzyna Woźnica; Kazimierz Niemczyk; Krzysztof Jamroziak Journal: J Clin Med Date: 2022-07-28 Impact factor: 4.964