| Literature DB >> 2574731 |
Abstract
Each H1-receptor antagonist has unique pharmacokinetic and pharmacodynamic properties, and each H1-antagonist has unique potency and potential for causing adverse effects. Some of the first-generation H1-receptor antagonists should no longer be used because their relative lack of efficacy is combined with a high potential for causing adverse effects. Some of the new H1-receptor antagonists, in manufacturers' recommended doses, seldom cause sedation but may have only modest potency. The choice of optimal H1-receptor antagonist treatment for each patient should be based on up-to-date clinical pharmacology information.Entities:
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Year: 1989 PMID： 2574731 DOI： 10.1016/0091-6749(89)90377-1
Source DB: PubMed Journal: J Allergy Clin Immunol ISSN： 0091-6749 Impact factor: 10.793