| Literature DB >> 25744824 |
J Broichhagen1, J A Frank, N R Johnston, R K Mitchell, K Šmid, P Marchetti, M Bugliani, G A Rutter, D Trauner, D J Hodson.
Abstract
Azobenzene photoresponsive elements can be installed on sulfonylureas, yielding optical control over pancreatic beta cell function and insulin release. An obstacle to such photopharmacological approaches remains the use of ultraviolet-blue illumination. Herein, we synthesize and test a novel yellow light-activated sulfonylurea based on a heterocyclic azobenzene bearing a push-pull system.Entities:
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Year: 2015 PMID： 25744824 PMCID： PMC6101206 DOI： 10.1039/c5cc01224d
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222