Literature DB >> 25743188

Development and leading-edge application of innovative photoaffinity labeling.

Yasumaru Hatanaka1.   

Abstract

Photoaffinity labeling has become increasingly important with the development of powerful specific probes that are synthesized by installing a photo-activatable functional group (photophore) on the framework of biological ligands. The present review summarizes the development of diazirine-based photoaffinity labeling by focusing on its application to the structural elucidation of ligand-accepting sites within proteins.

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Year:  2015        PMID： 25743188     DOI： 10.1248/cpb.c14-00645

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


  7 in total

1.  Peptidoglycan Metabolite Photoaffinity Reporters Reveal Direct Binding to Intracellular Pattern Recognition Receptors and Arf GTPases.

Authors:  Yen-Chih Wang; Nathan P Westcott; Matthew E Griffin; Howard C Hang
Journal:  ACS Chem Biol       Date:  2019-02-20       Impact factor: 5.100

2.  Asymmetric Synthesis of Photophore-Containing Lactisole Derivatives to Elucidate Sweet Taste Receptors.

Authors:  Tomoya Nakagita; Akiko Ishida; Zetryana Puteri Tachrim; Lei Wang; Takumi Misaka; Makoto Hashimoto
Journal:  Molecules       Date:  2020-06-17       Impact factor: 4.411

3.  Base-Mediated One-Pot Synthesis of Aliphatic Diazirines for Photoaffinity Labeling.

Authors:  Lei Wang; Zetryana Puteri Tachrim; Natsumi Kurokawa; Fumina Ohashi; Yasuko Sakihama; Yasuyuki Hashidoko; Makoto Hashimoto
Journal:  Molecules       Date:  2017-08-22       Impact factor: 4.411

4.  Design, Synthesis, and Evaluation of a Diazirine Photoaffinity Probe for Ligand-Based Receptor Capture Targeting G Protein-Coupled Receptors.

Authors:  Frederike M Müskens; Richard J Ward; Dominik Herkt; Helmus van de Langemheen; Andrew B Tobin; Rob M J Liskamp; Graeme Milligan
Journal:  Mol Pharmacol       Date:  2018-12-04       Impact factor: 4.436

5.  Photo-Brook rearrangement of acyl silanes as a strategy for photoaffinity probe design.

Authors:  Annika C S Page; Spencer O Scholz; Katherine N Keenan; Jessica N Spradlin; Bridget P Belcher; Scott M Brittain; John A Tallarico; Jeffrey M McKenna; Markus Schirle; Daniel K Nomura; F Dean Toste
Journal:  Chem Sci       Date:  2022-03-11       Impact factor: 9.825

Review 6.  Recent progress in the use of diaziridine-based sweetener derivatives to elucidate the chemoreception mechanism of the sweet taste receptor.

Authors:  Makoto Hashimoto; Tomoya Nakagita; Takumi Misaka
Journal:  RSC Adv       Date:  2021-10-01       Impact factor: 3.361

7.  Synthesis of Arylazide- and Diazirine-Containing CrAsH-EDT2 Photoaffinity Probes.

Authors:  Shameem S Syeda; Daren Rice; Derek J Hook; Leslie L Heckert; Gunda I Georg
Journal:  Arch Pharm (Weinheim)       Date:  2016-03-07       Impact factor: 3.751
  7 in total

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