| Literature DB >> 25742608 |
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Abstract
Entities:
Year: 2015 PMID: 25742608 PMCID: PMC4351095 DOI: 10.1371/journal.pgen.1005033
Source DB: PubMed Journal: PLoS Genet ISSN: 1553-7390 Impact factor: 5.917
Fig 4Exome sequencing analysis of KCL-22M vs KCL-22 cells.
(A, B) Chromosomal distribution of point mutation (A) and indel (B) hot spots identified specifically in KCL-22M cells. The counts of point mutation or indel events in 1 Mb windows along each chromosome were drawn. (C) Venn diagram analysis of significant gene expression probe sets from Fig. 1A, point mutations and indels in coding exons. The numbers included 160 annotated probes from the 245 expression probe sets, 194 unique genes for a total of 208 point mutations in coding exons, and 56 accession numbers for a total of 33 unique genes bearing frame-shift indels in coding exons. None of 7 overlapping genes were on chromosome 4.