BACKGROUND: Cellulite refers to the dimpled appearance of skin occurring where the dermis is tethered by subcutaneous fibrous septa arranged perpendicularly to the skin surface. OBJECTIVE: To demonstrate the safety and efficacy of a new system for vacuum-assisted precise tissue release for the treatment of cellulite. MATERIALS AND METHODS: Adult women with moderate to severe cellulite (N = 55) underwent a single treatment. Post-treatment assessments were performed after 3 and 14 days; 1, 3, and 6 months; and at 1 year. Outcome measures included blinded assessments of subject photographs, a validated Cellulite Severity Scale (CSS), and the Global Aesthetic Improvement Scale. Subject satisfaction and pain ratings were also recorded. RESULTS: The mean baseline CSS score of 3.4 decreased to 1.3 at 3 months (p < .0001) and 1.4 at 1 year (p < .0001), with 47 subjects (93%) having ≥1-point improvements. Subject satisfaction was 85% at 3 months and 94% at 1 year. Transient treatment-related adverse events were mild in severity. CONCLUSION: This study demonstrates the safety, efficacy, and subject satisfaction with vacuum-assisted precise tissue release in the treatment of cellulite. There was no reduction in treatment benefits for up to 1 year. These results supported the Food and Drug Administration clearance of the device for the long-term reduction in the appearance of cellulite.
BACKGROUND: Cellulite refers to the dimpled appearance of skin occurring where the dermis is tethered by subcutaneous fibrous septa arranged perpendicularly to the skin surface. OBJECTIVE: To demonstrate the safety and efficacy of a new system for vacuum-assisted precise tissue release for the treatment of cellulite. MATERIALS AND METHODS: Adult women with moderate to severe cellulite (N = 55) underwent a single treatment. Post-treatment assessments were performed after 3 and 14 days; 1, 3, and 6 months; and at 1 year. Outcome measures included blinded assessments of subject photographs, a validated Cellulite Severity Scale (CSS), and the Global Aesthetic Improvement Scale. Subject satisfaction and pain ratings were also recorded. RESULTS: The mean baseline CSS score of 3.4 decreased to 1.3 at 3 months (p < .0001) and 1.4 at 1 year (p < .0001), with 47 subjects (93%) having ≥1-point improvements. Subject satisfaction was 85% at 3 months and 94% at 1 year. Transient treatment-related adverse events were mild in severity. CONCLUSION: This study demonstrates the safety, efficacy, and subject satisfaction with vacuum-assisted precise tissue release in the treatment of cellulite. There was no reduction in treatment benefits for up to 1 year. These results supported the Food and Drug Administration clearance of the device for the long-term reduction in the appearance of cellulite.
Authors: Roberto Amore; Domenico Amuso; Vincenza Leonardi; Andrea Sbarbati; Giamaica Conti; Maria Albini; Francesco Leva; Ferdinando Terranova; Antonio Guida; Konstantinos Gkritzalas; Liya Gavashely; Roman Velichenko Journal: Plast Reconstr Surg Glob Open Date: 2018-05-18
Authors: Joely Kaufman-Janette; John H Joseph; Michael S Kaminer; James Clark; Sabrina G Fabi; Michael H Gold; Mitchel P Goldman; Bruce E Katz; Kappa Peddy; Joel Schlessinger; V Leroy Young; Matthew Davis; David Hurley; Genzhou Liu; Michael P McLane; Saji Vijayan; Lawrence S Bass Journal: Dermatol Surg Date: 2021-05-01 Impact factor: 2.914
Authors: Elizabeth L Tanzi; Christopher C Capelli; David W Robertson; Brenda LaTowsky; Carolyn Jacob; Omer Ibrahim; Michael S Kaminer Journal: Lasers Surg Med Date: 2021-07-05
Authors: Joel L Cohen; Neil S Sadick; M Todd Kirby; Michael P McLane; William R Lenderking; Randall H Bender; Jun Chen; David Hurley; Naomi B Knoble; Genzhou Liu; Qinfang Xiang; Jeffrey A Davidson; Mitchel P Goldman Journal: Dermatol Surg Date: 2020-12 Impact factor: 2.914