Literature DB >> 25742278

Full-genome sequences of hepatitis B virus subgenotype D3 isolates from the Brazilian Amazon Region.

Natália Spitz1, Francisco C A Mello2, Natalia Motta Araujo1.   

Abstract

The Brazilian Amazon Region is a highly endemic area for hepatitis B virus (HBV). However, little is known regarding the genetic variability of the strains circulating in this geographical region. Here, we describe the first full-length genomes of HBV isolated in the Brazilian Amazon Region; these genomes are also the first complete HBV subgenotype D3 genomes reported for Brazil. The genomes of the five Brazilian isolates were all 3,182 base pairs in length and the isolates were classified as belonging to subgenotype D3, subtypes ayw2 (n = 3) and ayw3 (n = 2). Phylogenetic analysis suggested that the Brazilian sequences are not likely to be closely related to European D3 sequences. Such results will contribute to further epidemiological and evolutionary studies of HBV.

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Year:  2015        PMID： 25742278      PMCID： PMC4371232          DOI： 10.1590/0074-02760140426

Source DB:  PubMed          Journal:  Mem Inst Oswaldo Cruz        ISSN： 0074-0276            Impact factor:   2.743


  13 in total

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Review 4.  The clinical implications of hepatitis B virus genotype: Recent advances.

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Journal:  Infect Genet Evol       Date:  2011-04-22       Impact factor: 3.342

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10.  Hepatitis B virus genotypes circulating in Brazil: molecular characterization of genotype F isolates.

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  1 in total

1.  Genetic Diversity of the Hepatitis B Virus Subgenotypes in Brazil.

Authors:  Barbara V Lago; Marcia P do Espirito-Santo; Vanessa D Costa; Vanessa A Marques; Livia M Villar; Lia L Lewis-Ximenez; Elisabeth Lampe; Francisco C A Mello
Journal:  Viruses       Date:  2019-09-15       Impact factor: 5.048
  1 in total

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