Incidental Detection of Solitary Hepatic Metastasis by 99mTc-MDP and 18F-NaF PET/CT in a Patient With Osteosarcoma of the Tibia.

A 36-year-old woman with a history of left above-knee amputation caused by tibial osteosarcoma 3 years ago underwent static Tc-MDP bone scintigraphy to evaluate osseous metastases. Although no lesion in the bone was identified, the images showed an intense activity in the region of the liver. This activity was also shown subsequently by F-NaF and F-FDG PET/CT imaging as a partially calcified lesion in the anterior segment of the right lobe of the liver. Solitary hepatic metastasis form osteosarcoma was suspected and further implied by follow-up studies.