Literature DB >> 2574217

Increase in intracellular cysteine after exposure to dithiothreitol: implications in radiobiology.

M F Dennis1, M R Stratford, P Wardman, R R Watfa.   

Abstract

Dithiothreitol reduces cystine in tissue-culture medium, and the resulting cysteine is accumulated in Chinese hamster V79 cells to an extent which should be taken into account in evaluating models of radiosensitivity and the effects of thiol radioprotectors.

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Year:  1989        PMID: 2574217     DOI: 10.1080/09553008914552351

Source DB:  PubMed          Journal:  Int J Radiat Biol        ISSN: 0955-3002            Impact factor:   2.694


  3 in total

1.  Regulation of CD20 expression by radiation-induced changes in intracellular redox status.

Authors:  Damodar Gupta; Meredith E Crosby; Alexandru Almasan; Roger M Macklis
Journal:  Free Radic Biol Med       Date:  2007-11-01       Impact factor: 7.376

Review 2.  Nitroimidazoles as hypoxic cell radiosensitizers and hypoxia probes: misonidazole, myths and mistakes.

Authors:  Peter Wardman
Journal:  Br J Radiol       Date:  2018-03-20       Impact factor: 3.039

3.  Dithiothreitol causes toxicity in C. elegans by modulating the methionine-homocysteine cycle.

Authors:  Gokul G; Jogender Singh
Journal:  Elife       Date:  2022-04-19       Impact factor: 8.713

  3 in total

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