| Literature DB >> 25741973 |
Ronald van Toorn1, Anne-Marie du Plessis, Hendrik Simon Schaaf, Heliose Buys, Richard H Hewlett, Johan F Schoeman.
Abstract
Neurologic tuberculous pseudoabscesses that clinically progress despite conventional antituberculosis therapy may be responsive to adjuvant thalidomide, a potent tumor necrosis factor-α inhibitor. In this study, the addition of thalidomide provided substantial clinical benefit in the majority of patients, and magnetic resonance imaging evolution of lesions from early-stage "T2 bright" with edema to "T2 black" represented a marker of cure.Entities:
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Year: 2015 PMID： 25741973 DOI： 10.1097/INF.0000000000000539
Source DB: PubMed Journal: Pediatr Infect Dis J ISSN： 0891-3668 Impact factor: 2.129